Amoxicillin - Revision history

Zeki at 01:33, 25 November 2024

2024-11-25T01:33:48Z

← Older revision		Revision as of 21:33, 24 November 2024
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	[[Category: Drugs]][[Category: Beta-Lactam Antibiotics]][[Category: ~~Aminopenicillin antibiotic~~]]		[[Category: Drugs]][[Category: Beta-Lactam Antibiotics]][[Category: Penicillins]]

	[[:Category: Antibiotics \| '''Oral Antibiotics''']]		[[:Category: Antibiotics \| '''Oral Antibiotics''']]

Zeki at 01:33, 25 November 2024

2024-11-25T01:33:28Z

← Older revision		Revision as of 21:33, 24 November 2024
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	[[:Category: Antibiotics \| '''Oral Antibiotics''']]		[[:Category: Antibiotics \| '''Oral Antibiotics''']]

	'''Drug class: [[:Category: Beta-Lactam Antibiotics \| β-Lactam Antibiotics]]''', belonging to the '''[[:Category: ~~Aminopenicillin antibiotic~~ \| ~~aminopenicillin~~]]''' ~~class of the penicillin~~ family		'''Drug class: [[:Category: Beta-Lactam Antibiotics \| β-Lactam Antibiotics]]''', belonging to the aminopenicillin class of the '''[[:Category: Penicillins \| penicillin]]''' family

	'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）		'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）

Zeki at 08:24, 14 November 2024

2024-11-14T08:24:58Z

← Older revision		Revision as of 04:24, 14 November 2024
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	[[Category: Drugs]][[Category: Beta-Lactam Antibiotics]]		[[Category: Drugs]][[Category: Beta-Lactam Antibiotics]][[Category: Aminopenicillin antibiotic]]

	[[:Category: Antibiotics \| '''Oral Antibiotics''']]		[[:Category: Antibiotics \| '''Oral Antibiotics''']]

Zeki at 08:24, 14 November 2024

2024-11-14T08:24:19Z

← Older revision		Revision as of 04:24, 14 November 2024
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	[[:Category: Antibiotics \| '''Oral Antibiotics''']]		[[:Category: Antibiotics \| '''Oral Antibiotics''']]

	'''Drug class: [[:Category: Beta-Lactam Antibiotics \| β-Lactam Antibiotics]]''', belonging to the [[:Category: Aminopenicillin antibiotic \| aminopenicillin]] class of the penicillin family		'''Drug class: [[:Category: Beta-Lactam Antibiotics \| β-Lactam Antibiotics]]''', belonging to the '''[[:Category: Aminopenicillin antibiotic \| aminopenicillin]]''' class of the penicillin family

	'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）		'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）

Zeki at 08:24, 14 November 2024

2024-11-14T08:24:01Z

← Older revision		Revision as of 04:24, 14 November 2024
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	[[:Category: Antibiotics \| '''Oral Antibiotics''']]		[[:Category: Antibiotics \| '''Oral Antibiotics''']]

	'''Drug class: [[:Category: Beta-Lactam Antibiotics \| β-Lactam Antibiotics]]''', belonging to the aminopenicillin class of the penicillin family		'''Drug class: [[:Category: Beta-Lactam Antibiotics \| β-Lactam Antibiotics]]''', belonging to the [[:Category: Aminopenicillin antibiotic \| aminopenicillin]] class of the penicillin family

	'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）		'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）

Zeki: /* FAQ */

2024-09-16T04:19:05Z

FAQ

← Older revision		Revision as of 00:19, 16 September 2024
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	Avoid alcohol and inform your doctor of any other medications, especially hormonal contraceptives.		Avoid alcohol and inform your doctor of any other medications, especially hormonal contraceptives.

	''''What Happens if I Miss a Dose?		'''What Happens if I Miss a Dose?

	Take the missed dose as soon as remembered unless it is close to the next dose. Do not double up on doses.		Take the missed dose as soon as remembered unless it is close to the next dose. Do not double up on doses.

Zeki at 01:39, 16 September 2024

2024-09-16T01:39:43Z

← Older revision		Revision as of 21:39, 15 September 2024
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	[[:Category: Antibiotics \| '''Oral Antibiotics''']]		[[:Category: Antibiotics \| '''Oral Antibiotics''']]

	'''Drug class: [[:Category: Beta-Lactam Antibiotics \| β-Lactam Antibiotics]]		'''Drug class: [[:Category: Beta-Lactam Antibiotics \| β-Lactam Antibiotics]]''', belonging to the aminopenicillin class of the penicillin family

	'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）		'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）

Zeki at 01:37, 16 September 2024

2024-09-16T01:37:22Z

← Older revision		Revision as of 21:37, 15 September 2024
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	'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）		'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）
	==Common Strengths of Amoxicillin]]		==Common Strengths of Amoxicillin==
	Amoxicillin are available in the following strengths:		Amoxicillin are available in the following strengths:
	*250 mg		*250 mg

Zeki at 01:37, 16 September 2024

2024-09-16T01:37:00Z

← Older revision		Revision as of 21:37, 15 September 2024
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	'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）		'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）
			==Common Strengths of Amoxicillin]]
			Amoxicillin are available in the following strengths:
			*250 mg
			*500 mg
			*875 mg (extended-release)
			*Available in liquid formulations (e.g. 125 mg/5 mL, 200 mg/5 mL, 400 mg/5 mL) for pediatric use.

			==Drug Trade Name of Amoxicillin==
			Amoxil

			==Drug Usage==
			Amoxicillin is prescribed for treating infections caused by susceptible bacteria, including:
			*Respiratory tract infections (e.g. pneumonia, bronchitis)
			*Ear, nose, and throat infections (e.g. otitis media, tonsilitis)
			*Skin infections
			*Urinary tract infections
			*Helicobacter pylori eardication in combination therapies for peptic ulcers

			==Mechanism of Action==
			Amoxicillin works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is effective against a range of gram-positive and some gram-negative bacteria.

			==Route of Administration==
			*Oral (tablets, capsules, liquid suspension)
			*Intramuscular injection
			*Intravenous (IV) bolus injection

			==Dosages==
			*Typically 500 mg every 12 hours or 250 mg every 8 hours.
			*Renal Impairment: Dosage adjustments are necessary based on estimated Glomerular Filtration Rate (eGFR):
			**eGFR >30 mL/min: No adjustment needed.
			**eGFR 10-30 mL/min: 250 mg every 12 hours.
			**eGFR <10 mL/min: 250 mg every 24 hours.

			==Side Effects==
			{\| class="wikitable"
			!style="text-align: left"\| Frequency
			!Adverse reactions
			\|-
			\| '''Common Side Effects
			\| Diarrhea, nausea, vomiting, rash, headache, and yeast infections.
			\|-
			\| rowspan="4" \| '''Serious Side Effects
			\| Allergic reaction (anaphylaxis)
			\|-
			\| Severe skin reactions (Stevens-Johnson syndrome)
			\|-
			\| Liver dysfunction
			\|-
			\| Clostridium difficile-associated diarrhea
			\|}

			==Pharmacokinetics==
			*Bioavailability: Approximately 95% when taken only.
			*Peak Concnetrations: After oral administration, peak serum concentrations typically occur 1 to 2 hours post-dose.
			*Half-Life: The elimination half-life of amoxicillin is about 1 hour, which is relatively short. This necessitates multiple dosing throughout the day to maintain effective therapeutic levels.
			*Excretion: About 60% of an orall administered dose is excreted unchanged in the urine within 6 to 8 hours.
			*Onset of Action: Typically within 1-2 hours.
			*Duration: Effects can last 8-12 hours, necessitating multiple doses per day.

			==Drug Precautions==
			'''Pregnancy

			Generally considered safe; however, consult a doctor.

			'''Breastfeeding

			Excreted in breast milk; caution is advised.

			'''Children and Elderly

			Safe for use in children; elderly patients may require dosage adjstments based on renal function.

			'''Monitoring Requirements

			Regular monitoring of renal function, liver enzymes, and signs of severe allergic reactions is recommended.

			'''Drug Interactions
			*Anticoagulants: Amoxicillin can enhance the effects of anticoagulants like warfarin, leading to an increased risk of bleeding.
			*Allopurinol: When taken together, amoxicillin and allopurinol may increase the incidence of skin rashes.
			*Methotrexate: Amoxicillin may interfere with the elimination of methotrexate, potentially increasing its toxicity.
			*Oral Contraceptives: Amoxicillin can affect gut flora, potentially leading to reduced efficacy of combined oral contraceptives. Patients using hormonal contraceptives should be informed about this risk and consider additional contraceptive measures during amoxicillin therapy.
			*Food Interactions: While food dose not significantly affect the absorption of amoxicillin, it is generally advised to take it with food to minimize gastrointestinal side effects.

			==FAQ==
			'''How Should I Take the Tablet?

			Swallow whole' chewable tablets should be chewed thoroughly. Liquid forms can be mixed with cold beverages.

			'''What Should I Avoid While Taking?

			Avoid alcohol and inform your doctor of any other medications, especially hormonal contraceptives.

			''''What Happens if I Miss a Dose?

			Take the missed dose as soon as remembered unless it is close to the next dose. Do not double up on doses.

Zeki: Created page with "Category: DrugsCategory: Beta-Lactam Antibiotics '''Oral Antibiotics''' '''Drug class: :Category: Beta-Lactam Antibiotics | β-Lactam..."

2024-09-16T01:05:55Z

Created page with "Category: Drugs Category: Beta-Lactam Antibiotics '''Oral Antibiotics''' '''Drug class: :Category: Beta-Lactam Antibiotics | β-Lactam..."

New page

[[Category: Drugs]][[Category: Beta-Lactam Antibiotics]]

[[:Category: Antibiotics | '''Oral Antibiotics''']]

'''Drug class: [[:Category: Beta-Lactam Antibiotics | β-Lactam Antibiotics]]

'''Amoxicillin (AMOXIL)'''（中文：[[阿莫西林]]）