Apixaban - Revision history

Zeki: /* Route of AdministrationR */

2024-07-11T01:35:35Z

Route of AdministrationR

← Older revision		Revision as of 21:35, 10 July 2024
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	Direct Factor Xa inhibitors is a selective clotting factor Xa (FXa) inhibitor, preventing the formation of blood clots		Direct Factor Xa inhibitors is a selective clotting factor Xa (FXa) inhibitor, preventing the formation of blood clots

	==Route of ~~AdministrationR~~==		==Route of Administration==
	Oral		Oral

Zeki: /* Drug Usage */

2024-07-11T01:31:01Z

Drug Usage

← Older revision		Revision as of 21:31, 10 July 2024
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	*Reduce risk of recurrent DVT and PE		*Reduce risk of recurrent DVT and PE

	==Mechanism of Action''		==Mechanism of Action==
	Direct Factor Xa inhibitors is a selective clotting factor Xa (FXa) inhibitor, preventing the formation of blood clots		Direct Factor Xa inhibitors is a selective clotting factor Xa (FXa) inhibitor, preventing the formation of blood clots

Zeki at 07:42, 8 July 2024

2024-07-08T07:42:30Z

← Older revision		Revision as of 03:42, 8 July 2024
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	[[Category: Drugs]][[Category: Direct Factor Xa ~~inhibitors~~]]		[[Category: Drugs]][[Category: Direct Factor Xa inhibitor]]

	[[:Category: Anticoagulant Drug \| '''Anticoagulant Drug''']]		[[:Category: Anticoagulant Drug \| '''Anticoagulant Drug''']]

Zeki at 07:05, 8 July 2024

2024-07-08T07:05:34Z

← Older revision		Revision as of 03:05, 8 July 2024
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	'''Apixaban (ELIQUIS)'''（中文：[[阿哌沙班]]）		'''Apixaban (ELIQUIS)'''（中文：[[阿哌沙班]]）
			==Common Strengths of Apixaban Tablet==
			Apixaban Tablet are available in the following strengths:
			*2.5 mg and 5 mg tablets

			==Drug Trade Names of Apixaban Tablet==
			Eliquis

			==Drug Usage==
			*Reduce risk of stroke and systemic embolism in nonvalvular atrial fibrillation
			*Prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) after hip or knee replacement surgery
			*Reduce risk of recurrent DVT and PE

			==Mechanism of Action''
			Direct Factor Xa inhibitors is a selective clotting factor Xa (FXa) inhibitor, preventing the formation of blood clots

			==Route of AdministrationR==
			Oral

			==Dosages==
			*Nonvalvular atrial fibrillation: 5 mg orally twice daily
			*DVT/PE prevention after surgery: 2.5 mg orally twice daily
			*DVT/PE treatment: 10 mg orally twice daily for 7 days, then 5 mg twice daily
			*Reduce risk of recurrent DVT/PE: 2.5 mg orally twice daily

			==Side Effects==
			{\| class="wikitable"
			!style="text-align: left"\| Frequency
			!Adverse reactions
			\|-
			\| rowspan="3" \| '''Common
			\| Easy bruising
			\|-
			\| Anemia
			\|-
			\| Nausea
			\|-
			\| rowspan="4" \| '''Uncommon
			\| Thrombocytopenia
			\|-
			\| Allergic reactions
			\|-
			\| Hypotension
			\|-
			\| Intracranial hemorrhage
			\|}

			==Pharmacokinetics==
			*Absorption
			**It is rapidly absorbed, with maximum concentration occurring 3-4 hours after oral administration
			*Metabolism and Elimination
			**Apixaban is eliminated through multiple pathways, including metabolism, biliary excretion, and direct intestinal excretion
			*half-life of approximately
			** 12 hours

			==Drug Precautions==
			'''Pregnancy

			Not recommended

			'''Breastfeeding

			Not recommended

			'''Monitoring Requirements

			Signs and symptoms of bleeding:
			*Unexpected bleeding or bleeding that lasts a long time
			*Unusual bruising, nosebleeds, bleeding gums
			*Pink/brown urine, red/black stools
			*Coughing up blood or blood clots
			*Vomiting blood or vomit that looks like coffee grounds

			'''Drug Interactions

			Interacts with other blood thinners, NSAID, antidepressants, and certain herbal products like St. Johin's wort

			'''Caution

			Use with caution in patients at risk of bleeding, or taking concomitant drugs that increase risk of bleeding.

			==FAQ==
			'''How Should I Take the Tablet?

			Take with or without food, usually twice daily

			'''What Should I Avoid While Taking?

			Avoid activities with a high risk of injury or bleeding

			'''What Happens if I Miss a Dose?

			Take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next scheduled dose

Zeki at 06:23, 8 July 2024

2024-07-08T06:23:08Z

← Older revision		Revision as of 02:23, 8 July 2024
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	[[:Category: Anticoagulant Drug \| '''Anticoagulant Drug''']]		[[:Category: Anticoagulant Drug \| '''Anticoagulant Drug''']]

	'''Drug class: [[:Category: Direct Factor Xa ~~inhibitors~~ \| Direct Factor Xa ~~inhibitors~~]]		'''Drug class: [[:Category: Direct Factor Xa inhibitor \| Direct Factor Xa inhibitor]]

	'''Apixaban (ELIQUIS)'''（中文：[[阿哌沙班]]）		'''Apixaban (ELIQUIS)'''（中文：[[阿哌沙班]]）

Zeki: Created page with "Category: DrugsCategory: Direct Factor Xa inhibitors '''Anticoagulant Drug''' '''Drug class: :Category: Direct Factor Xa inhibi..."

2024-07-08T06:21:05Z

Created page with "Category: Drugs Category: Direct Factor Xa inhibitors '''Anticoagulant Drug''' '''Drug class: :Category: Direct Factor Xa inhibi..."

New page

[[Category: Drugs]][[Category: Direct Factor Xa inhibitors]]

[[:Category: Anticoagulant Drug | '''Anticoagulant Drug''']]

'''Drug class: [[:Category: Direct Factor Xa inhibitors | Direct Factor Xa inhibitors]]

'''Apixaban (ELIQUIS)'''（中文：[[阿哌沙班]]）