Candesartan - Revision history

Zeki at 02:52, 5 September 2024

2024-09-05T02:52:17Z

← Older revision		Revision as of 22:52, 4 September 2024
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	==Pronunciation==		==Pronunciation==
	===Candesartan cilexetil Tablet 4mg===		===Candesartan cilexetil Tablet 4mg===
	[[File:.mp3]]		[[File:Candesartan cilexetil Tablet 4mg.mp3]]

	==Common Strengths of Candesartan==		==Common Strengths of Candesartan==

Zeki at 02:51, 5 September 2024

2024-09-05T02:51:33Z

← Older revision		Revision as of 22:51, 4 September 2024
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	'''Drug class: [[:Category: Angiotensin II receptor Blockers ARB \| Angiotensin II Receptor Blockers, ARB]]		'''Drug class: [[:Category: Angiotensin II receptor Blockers ARB \| Angiotensin II Receptor Blockers, ARB]]

	'''Candesartan''' (中文：[[坎地沙坦]])		'''Candesartan (BLOPRESS)''' (中文：[[坎地沙坦]])
	==Pronunciation==		==Pronunciation==
	===Candesartan cilexetil Tablet 4mg===		===Candesartan cilexetil Tablet 4mg===

Zeki at 01:55, 5 September 2024

2024-09-05T01:55:05Z

← Older revision		Revision as of 21:55, 4 September 2024
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	[[Category: Drugs]][[Category:Angiotensin II receptor Blockers ARB]]		[[Category: Drugs]][[Category:Angiotensin II receptor Blockers ARB]]

			[[:Category: Cardiovascular Drug \| '''Cardiovascular Drug''']]

			'''Drug class: [[:Category: Angiotensin II receptor Blockers ARB \| Angiotensin II Receptor Blockers, ARB]]

	'''Candesartan''' (中文：[[坎地沙坦]])		'''Candesartan''' (中文：[[坎地沙坦]])

Zeki at 03:15, 21 June 2024

2024-06-21T03:15:18Z

← Older revision		Revision as of 23:15, 20 June 2024
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	[[Category: Drugs]]		[[Category: Drugs]][[Category:Angiotensin II receptor Blockers ARB]]

	'''Candesartan''' (中文：[[坎地沙坦]])		'''Candesartan''' (中文：[[坎地沙坦]])

Zeki: /* Drug Management */

2024-06-21T02:55:24Z

Drug Management

← Older revision		Revision as of 22:55, 20 June 2024
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	'''Beast Feeding		'''Beast Feeding

	~~The~~ are not recommended.		They are not recommended.

	'''Hepatic Impairment		'''Hepatic Impairment

Zeki: /* Side Effects */

2024-06-21T02:46:17Z

Side Effects

← Older revision		Revision as of 22:46, 20 June 2024
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	\| Dizziness		\| Dizziness
	\|-		\|-
	\| ~~Hadache~~		\| Headache
	\|-		\|-
	\| Cough		\| Cough

Zeki: /* FAQs */

2024-06-21T02:22:27Z

FAQs

← Older revision		Revision as of 22:22, 20 June 2024
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	If you forget to take a dose and you usually take candesartan:		If you forget to take a dose and you usually take candesartan:
	*Once a day: Take i as soon as you remember unless it is less than 12 hours until your next dose. In this case leave out the missed dose and take your next dose at the usual time.		*Once a day: Take it as soon as you remember unless it is less than 12 hours until your next dose. In this case leave out the missed dose and take your next dose at the usual time.
	Never take 2 doses to make up for a forgotten one.		Never take 2 doses to make up for a forgotten one.

Zeki at 02:21, 21 June 2024

2024-06-21T02:21:56Z

← Older revision		Revision as of 22:21, 20 June 2024
Line 5:		Line 5:
	===Candesartan cilexetil Tablet 4mg===		===Candesartan cilexetil Tablet 4mg===
	[[File:.mp3]]		[[File:.mp3]]

			==Common Strengths of Candesartan==
			Candesartan is available in the following strengths:
			*4 mg
			*8 mg
			*16 mg
			*32 mg

			==Drug Trade Names of Candesartan==
			The brand names for Candesartan is Blopress.

			==Mechanism of Action==
			Candesartan is an angiotensin II receptor blocker.

			Candesartan relaxes and widens your blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. It is used to treat high blood pressure and heart failure. It helps to prevent future strokes, heart attacks and kidney problems. It also improves your survival if you are taking it for heart failure.

			==Route of Administration==
			Candesartan is given orally as the ester prodrug candesartan cilexetil which is rapidly converted to the active substance candesartan during absorption from the gastrointestinal tract.

			Onset of antihypertensive action occurs about 2 hour after a dose and the maximum effect is achieved within about 4 weeks of starting therapy.

			==Dosages==
			For Adult
			*High blood pressure
			**8 mg to 32 mg once a day
			*Heart failure
			**4 mg to 32 mg once a day
			For Children (aged 6 years and over) treat high blood pressure
			*Weighing less than 50 kg
			**4 mg to 8 mg once a day
			*Weighing 50 kg or more
			**4 mg to 16 mg once a day

			==Side Effects==
			{\| class="wikitable"
			!style="text-align: left"\| Frequency
			!Adverse reactions
			\|-
			\| rowspan="2" \|'''Common (≥1/100 to <1/10)
			\| Hypotension
			\|-
			\| Hyperkalemia
			\|-
			\| rowspan="7" \|'''Very rare (<1/10,000)
			\| Dizziness
			\|-
			\| Hadache
			\|-
			\| Cough
			\|-
			\| Pruritus
			\|-
			\| Rash
			\|-
			\| Nausea
			\|-
			\| Hyponatremia
			\|}

			==Pharmacokinetics==
			*Following oral administration, candesartan cilexetil is converted to the active substance candesartan.
			*Peak serum concentrations occur about 3 to 4 hours following tablet intake.
			*The bioavailability of candesartan is not affected by food.
			*It is excreted in urine and bile mainly as unchanged drug with a small amount as inactive metabolites.
			*The terminal elimination half-life is about 9 hours.

			==Drug Management==
			'''Pregnancy

			Should be avoided in pregnancy unless essential.

			'''Beast Feeding

			The are not recommended.

			'''Hepatic Impairment
			*Initially 4 mg once daily in mild or moderate impairment.
			*Avoid in severe hepatic impairment.

			'''Renal Impairment
			*Use with caution if eGFR < 15 mL/minute/1.73m<sup>2</sup>
			**Initially 4 mg daily.

			'''Monitoring Requirements

			Monitor plasma-potassium concentration, particularly in the elderly and in patients with renal impairment.

			'''Drug Interaction
			*Diuretics
			**Enhanced hypotensive effect when given with diuretics
			*Potassium sparing diuretics (triamterene, amiloride and spironolactone) or Potassium supplement
			**Increase risk of hyperkalemia

			'''Caution
			*Aortic or mitral valve stenosis
			*Hypertrophic cardiomyopathy
			*Patients with a history of angioedema
			*Patients with a primary aldosteronism

			'''Contraindication
			*Cholestasis

			==FAQs==
			'''How should I take the tablet?

			Usually take candesartan tablet once a day, can take it at any time, with or without food. Swallow the tablet whole with a drink of water.

			'''What should I avoid while taking?

			Avoid potassium-containing salt substitutes or potassium supplements, unless your doctor has told you to.

			'''What happens if I miss a dose?

			If you forget to take a dose and you usually take candesartan:
			*Once a day: Take i as soon as you remember unless it is less than 12 hours until your next dose. In this case leave out the missed dose and take your next dose at the usual time.
			Never take 2 doses to make up for a forgotten one.

Zeki at 00:54, 21 June 2024

2024-06-21T00:54:48Z

← Older revision		Revision as of 20:54, 20 June 2024
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	[[Category: Drugs~~]][[Category:~~]]		[[Category: Drugs]]

	'''Candesartan''' (中文：[[坎地沙坦]])		'''Candesartan''' (中文：[[坎地沙坦]])

Zeki: Replaced content with "Category: DrugsCategory: '''Candesartan''' (中文：坎地沙坦) ==Pronunciation== ===Candesartan cilexetil Tablet 4mg=== File:.mp3"

2024-06-21T00:54:36Z

Replaced content with "Category: Drugs[[Category:]] '''Candesartan''' (中文：坎地沙坦) ==Pronunciation== ===Candesartan cilexetil Tablet 4mg=== File:.mp3"

← Older revision		Revision as of 20:54, 20 June 2024
Line 5:		Line 5:
	===Candesartan cilexetil Tablet 4mg===		===Candesartan cilexetil Tablet 4mg===
	[[File:.mp3]]		[[File:.mp3]]

	~~==Common Strengths of Candesartan==~~
	~~Candesartan is available in the following strengths:~~
	*4 mg
	*8 mg
	*16 mg
	*32 mg

	~~==Drug Trade Names of Candesartan==~~
	~~The brand names for candesartan is Blopress.~~

	~~==Mechanism of Action==~~
	~~Candesartan is an angiotensin II receptor blocker.~~

	~~Candesartan relaxes and widens your blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body.~~

	~~It is used to treat high blood pressure and heart failure. It helps to prevent future strokes, heart attacks and kidney problems. It also improves your survival if you are taking it for heart failure.~~

	~~==Route of Administration==~~
	~~Candesartan is given orally as the ester prodrug candesartan cilexetil which is rapidly converted to the active substance candesartan during absorption from the gastrointestinal tract.~~

	~~Onset of antihypertensive action occurs about 2 hours after a dose and the maximum effect is achieved within about 4 weeks of starting therapy.~~

	~~==Dosage==~~
	*For Adult
	**High blood pressure: 8 mg to 32 mg once a day
	**Heart failure: 4 mg to 32 mg once a day
	*For children (aged 6 years and over)
	**High blood pressure
	***Weighing less than 50 kg: 4 mg to 8 mg once a day
	***Weighing 50 kg or more: 4 mg to 16 mg once a day

	~~==Side Effects==~~
	~~{\| class="wikitable"~~
	~~!style="text-align: left"\| Frequency~~
	~~!Adverse reactions~~
	\|-
	~~\| rowspan="2" \| '''Common (≥1/100 to <1/10)~~
	~~\| Hypotension~~
	\|-
	~~\| Hyperkalemia~~
	\|-
	~~\| rowspan="7" \| '''Very Rare (<1/10,000)~~
	~~\| Dizziness~~
	\|-
	~~\| Headache~~
	\|-
	~~\| Cough~~
	\|-
	~~\| Pruritus~~
	\|-
	~~\| Rash~~
	\|-
	~~\| Nausea~~
	\|-
	~~\| Hyponatremia~~
	\|}

	~~==Pharmacokinetics==~~
	*Following oral administration, candesartan cilexetil is converted to the active substance candesartan.
	*Peak serum concentrations occur about 3 to 4 hours following tablet intake.
	*The bioavailability of candesartan is not affected by food.
	*It is excreted in urine and bile mainly as unchanged drug with a small amount as inactive metabolites.
	*The terminal elimination half-life is about 9 hours.

	~~==Drug Management==~~
	~~'''Pregnancy~~

	~~Should be avoided in pregnancy unless essential.~~

	~~'''Breast Feeding~~

	~~They are not recommended.~~

	~~'''Hepatic Impairment~~
	*Initially 4 mg once daily in mild or moderate impairment.
	*Avoid in severe hepatic impairment.

	~~'''Renal Impairment~~
	*Initially 4 mg daily.
	*Use with caution if eGFR < 15 mL/minute/1.73m2


	~~'''Monitoring Requirements~~

	~~Monitor plasma-potassium concentration, particularly in the elderly and in patients with renal impairment.~~

	~~'''Drug Interaction~~
	*Diuretics
	**Enhanced hypotensive effect when given with diuretics
	*Potassium sparing diuretics (triamterene, amiloride and spironolactone) or potassium supplement
	**Increase risk of hyperkalemia

	~~'''Caution~~
	*Aortic or mitral valve stenosis
	*Hypertrophic cardiomyopathy
	*Patients with a history of angioedema
	*Patients with primary aldosteronism

	~~'''Contraindication~~
	*Cholestasis

	~~==FAQs==~~
	~~'''How should I take the tablet?~~

	~~Usually take candesartan tablet once a day, can take it at any time, with or without food. Swallow the tablet whole with a drink of water.~~

	~~'''What should I avoid while taking?~~

	~~Avoid potassium-containing salt substitutes or potassium supplements, unless your doctor has told you to.~~

	~~'''What happens if I miss a dose?~~

	~~If you forget to take a dose and you usually take candesartan:~~
	*Once a day: take it as soon as you remember unless it is less than 12 hours until your next dose. In this case leave out the missed dose and take your next dose at the usual time.
	~~Never take 2 doses to make up for a forgotten one.~~