Carbamazepine - Revision history

Zeki at 05:31, 5 September 2024

2024-09-05T05:31:08Z

← Older revision		Revision as of 01:31, 5 September 2024
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	[[Category: Drugs]] [[Category:Seizures]]		[[Category: Drugs]][[Category: Anticonvulsant]] [[Category:Seizures]]

	[[:Category: Anticonvulsant \| '''Anticonvulsant''']]		[[:Category: Anticonvulsant \| '''Anticonvulsant''']]

Zeki at 05:30, 5 September 2024

2024-09-05T05:30:13Z

← Older revision		Revision as of 01:30, 5 September 2024
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	[[:Category: Anticonvulsant \| '''Anticonvulsant''']]		[[:Category: Anticonvulsant \| '''Anticonvulsant''']]

	'''Carbamazepine'''~~(中文:~~ [[卡馬西平]]~~) is~~ an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.		'''Carbamazepine'''（中文：[[卡馬西平]]）is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.
	It is used in schizophrenia and as a second-line agent in the management of bipolar disorder unresponsive to lithium.		It is used in schizophrenia and as a second-line agent in the management of bipolar disorder unresponsive to lithium.

Zeki at 05:29, 5 September 2024

2024-09-05T05:29:33Z

← Older revision		Revision as of 01:29, 5 September 2024
Line 1:		Line 1:
	[[Category: Drugs]] [[Category:Seizures]]		[[Category: Drugs]] [[Category:Seizures]]

	[[:Category: Anticonvulsant \| Anticonvulsant]]		[[:Category: Anticonvulsant \| '''Anticonvulsant''']]

	'''Carbamazepine'''(中文: [[卡馬西平]]) is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.		'''Carbamazepine'''(中文: [[卡馬西平]]) is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.

Zeki at 05:29, 5 September 2024

2024-09-05T05:29:18Z

← Older revision		Revision as of 01:29, 5 September 2024
Line 1:		Line 1:
	[[Category: Drugs]] [[Category:Seizures]]		[[Category: Drugs]] [[Category:Seizures]]

	[[:~~Cetagory~~: Anticonvulsant \| Anticonvulsant]]		[[:Category: Anticonvulsant \| Anticonvulsant]]

	'''Carbamazepine'''(中文: [[卡馬西平]]) is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.		'''Carbamazepine'''(中文: [[卡馬西平]]) is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.

Zeki at 05:27, 5 September 2024

2024-09-05T05:27:55Z

← Older revision		Revision as of 01:27, 5 September 2024
Line 1:		Line 1:
	[[Category: Drugs]] [[Category:Seizures]]		[[Category: Drugs]] [[Category:Seizures]]

			[[:Cetagory: Anticonvulsant \| Anticonvulsant]]

	'''Carbamazepine'''(中文: [[卡馬西平]]) is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.		'''Carbamazepine'''(中文: [[卡馬西平]]) is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.
	It is used in schizophrenia and as a second-line agent in the management of bipolar disorder unresponsive to lithium.		It is used in schizophrenia and as a second-line agent in the management of bipolar disorder unresponsive to lithium.

Helen: /* Pharmacokinetics */

2020-10-12T06:33:44Z

Pharmacokinetics

← Older revision		Revision as of 02:33, 12 October 2020
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	!style="text-align: left"\| Elimination half-life		!style="text-align: left"\| Elimination half-life
	\|Excreted in the urine almost entirely in the form of its metabolites; some are also excreted in faeces.		\|Excreted in the urine almost entirely in the form of its metabolites; some are also excreted in faeces.

	\|}		\|}

Helen: /* Drug Names */

2020-10-12T06:32:28Z

Drug Names

← Older revision		Revision as of 02:32, 12 October 2020
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	\|Carbamazepine Suspension 100mg/5ml		\|Carbamazepine Suspension 100mg/5ml
	\|CARB49		\|CARB49
			\|P1S1S3
			\|-
			\|Carbamazepine tablet 200mg
			\|CARB02
			\|P1S1S3
			\|-
			\|Carbamazepine CR tablet 200mg
			\|CARB51
	\|P1S1S3		\|P1S1S3
	\|}		\|}

Helen at 02:44, 9 October 2020

2020-10-09T02:44:50Z

← Older revision		Revision as of 22:44, 8 October 2020
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	[[Category: Drugs]] [[Category:~~Anticonvulsant medication~~]]		[[Category: Drugs]] [[Category:Seizures]]
	'''Carbamazepine'''(中文: [[卡馬西平]]) is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.		'''Carbamazepine'''(中文: [[卡馬西平]]) is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. Carbamazepine appears to work as well as phenytoin and valproate for focal and generalized seizures. It is not effective for absence or myoclonic seizures.
	It is used in schizophrenia and as a second-line agent in the management of bipolar disorder unresponsive to lithium.		It is used in schizophrenia and as a second-line agent in the management of bipolar disorder unresponsive to lithium.

Helen: /* Drug interaction */

2020-10-08T02:11:05Z

Drug interaction

← Older revision		Revision as of 22:11, 7 October 2020
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	\|Carbamazepine accelerates metabolism of thyroid hormones (may increase thyroxine dosage in hypothyroidism)		\|Carbamazepine accelerates metabolism of thyroid hormones (may increase thyroxine dosage in hypothyroidism)

			\|}

	\|}		===Caution===
			*avoid in patients with cardiac disease
			Genotype test for HLA-B1502 allele in Han Chinese of Thai origin (avoid Carbamazepine unless no alternative – risk of Stevens-Johnson syndrome in presence of HLA-B*1502 allele);
			*may exacerbate absence and myoclonic seizures
			*consider vitamin D supplement for immobilized patients or who have inadequate sun exposure or dietary intake of calcium
			*susceptibility to glaucoma
			*cross-sensitivity reported with oxcarbazepine and with phenytoin

			===Contraindications===
			*AV conduction abnormalities
			*History of bone-marrow depression
			*Acute porphyria

			===Hepatic impairment===
			Metabolism impaired in advanced liver disease.

			===Renal impairment===
			Use with caution

			===Pregnancy===
			Women of child-bearing potential should discuss with a specialist the impact of both epilepsy, and its treatment, on the outcome of pregnancy. There is an increased risk of teratogenicity associated with the use of antiepileptic drug (especially if used during the first trimester)

			===Breast-feeding===
			Use during breast feeding is not recommended.

			===Warning===
			This medicine may make you sleepy. If this happens, do not drive or use tools or machines
			Do not stop taking this medicine unless your doctor tells you to stop

			== FAQ ==
			=== How should I take the tablet? ===
			Donepezil tablet and orodispersible tablet should be taken orally at bedtime, or as directed by the doctor. The orodispersible tablet should be placed on the tongue and allowed to disperse before swallowing with or without water. Both formulations can be taken with or without food.
			=== What should I avoid while taking? ===
			Avoid abruptly discontinue the medication.
			=== What happen if I overdose? ===
			Contact your primary care doctor.
			If emergency situation, call 999
			=== What happen if I miss a dose? ===
			Take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Helen: /* Drug interaction */

2020-10-08T02:01:05Z

Drug interaction

@@ Line 111: / Line 111: @@
 erythromycin
 isoniazid
 |-
-!style="text-align: left"| Morphine
+|CYP3A4 inducers:
-|Morphine reduces the clearance of gabapentin; patients receiving both drugs should be monitored for signs for CNS depression and doses should be reduced accordingly.
+Rifampicin
 |}