Zeki at 02:15, 30 September 2024

2024-09-30T02:15:01Z

← Older revision		Revision as of 22:15, 29 September 2024
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	**For eGFR <10 mL/min, reduce the dose by three-quarters.		**For eGFR <10 mL/min, reduce the dose by three-quarters.

	~~==Side Effects==~~
	==Side Effects==		==Side Effects==
	{\| class="wikitable"		{\| class="wikitable"

Zeki at 01:30, 30 September 2024

2024-09-30T01:30:36Z

← Older revision		Revision as of 21:30, 29 September 2024
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	'''Cefaclor'''（中文：[[頭孢克洛]]）		'''Cefaclor'''（中文：[[頭孢克洛]]）
			==Common Strengths of Cefaclor==
			Cefaclor are available in the following strengths:
			*250 mg
			*500 mg

			==Drug Usage==
			Cefaclor is used to treat a variety of infections, including:
			*Respiratory tract infections (e.g. pneumonia)
			*Skin infections
			*Ear infections (otitis media)
			*Urinary tract infections

			==Mechanism of Action==
			Cefaclor exerts its antibacterial effect by inhibiting cell wall synthesis. It binds to specific penicillin-binding proteins (PBPs) within the bacterial cell wall, leading to cell lysis and death.

			==Route of Administration==
			Oral

			==Dosages==
			The usual dosages for cefaclor are as follows:
			*Normal Adults: 250 mg to 500 mg every 8 hours.
			*Children: 20 to 40 mg/kg/day divided every 8 hours, with a maximum of 1,500 mg/day.
			*Renal Impairment:
			**For patients with an eGFR of 10-30 mL/min, the dose may need to be reduced by half.
			**For eGFR <10 mL/min, reduce the dose by three-quarters.

			==Side Effects==
			==Side Effects==
			{\| class="wikitable"
			!style="text-align: left"\| Frequency
			!Adverse reactions
			\|-
			\| rowspan="5" \| '''Common Side Effects
			\| Diarrhea
			\|-
			\| Nausea
			\|-
			\| Vomiting
			\|-
			\| Rash
			\|-
			\| Headache
			\|-
			\| rowspan="5" \| '''Serious Side Effects
			\| Allergic reactions (e.g. hives, difficulty breathing)
			\|-
			\| Stevens-Johnson syndrome
			\|-
			\| Colitis
			\|-
			\| Severe skin reactions
			\|-
			\| Liver dysfunction
			\|}

			==Pharmacokinetics==
			*Bioavailability: Well absorbed after oral administration, with peak plasma concentrations reached within 30 to 60 minutes.
			*Half-life: The elimination half-life of cefaclor ranges from 0.6 to 0.9 hours.
			*Excretion: Cefaclor undergoes minimal metabolism, with about 60% to 85% of the drug excreted unchanged in the urine within 8 hours post-administration.

			==Drug Precautions==
			'''Pregnancy

			Cefaclor is generally considered safe during pregnancy, but it should only be used when necessary.

			'''Breastfeeding

			Cefaclor is excreted in breast milk; caution is advised when administering it to breastfeeding mothers.

			'''Children and Elderly

			Cefaclor can be prescribed to children, but precautions apply. Elderly patients may require careful monitoring.

			'''Monitoring Requirements

			Patients on cefaclor should be monitored for:
			*Signs of allergic reactions
			*Liver function tests
			*Renal function

			'''Drug Interactions

			Cefaclor may interact with:
			*Probenecid: Increases cefaclor levels by inhibiting renal excretion.
			*Warfarin: May enhance anticoagulant effects, necessitating monitoring of prothrombin time.

			==FAQ==
			'''How Should I Take the cefaclor?

			Take cefaclor as prescribed, with or without food. Swallow capsules whole with a glass of water.

			'''What Should I Avoid While Taking?

			Avoid alcohol if cefaclor causes nausea.

			'''What Happens if I Miss a Dose?

			If a dose is missed, take it as soon as remembered. If it is close to the next dose, skip the missed dose and resume the regular schedule. Do not double up on doses.

Zeki: Created page with "Category: DrugsCategory: Second Generation Cephalosporin Antibiotic '''Oral Antibiotics''' '''Drug class: :Category: Second Generation..."

2024-09-30T01:08:22Z

Created page with "Category: Drugs Category: Second Generation Cephalosporin Antibiotic '''Oral Antibiotics''' '''Drug class: :Category: Second Generation..."

New page

[[Category: Drugs]][[Category: Second Generation Cephalosporin Antibiotic]]

[[:Category: Antibiotics | '''Oral Antibiotics''']]

'''Drug class: [[:Category: Second Generation Cephalosporin Antibiotic | Second-Generation Cephalosporin Antibiotic]]''', belonging to the Cephalosporin class of antibiotics, specifically the second generation.

'''Cefaclor'''（中文：[[頭孢克洛]]）

Cefaclor - Revision history

Zeki at 02:15, 30 September 2024

Zeki at 01:30, 30 September 2024

Zeki: Created page with "Category: DrugsCategory: Second Generation Cephalosporin Antibiotic '''Oral Antibiotics''' '''Drug class: :Category: Second Generation..."