Diamorphine - Revision history

Ctol2: /* Side Effects */

2020-09-30T09:54:56Z

Side Effects

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	==Side Effects==		==Side Effects==
			===Opioid Analgesic in general===
	~~As for '''~~Opioid Analgesic
	in general

	The commonest adverse effects are nausea, vomiting, constipation, drowsiness and confusion.		The commonest adverse effects are nausea, vomiting, constipation, drowsiness and confusion.

	Large doses of opioids produce respiratory depression and hypotension, with circulatory failure and deepening coma. Death may occur from respiratory failure.		Large doses of opioids produce respiratory depression and hypotension, with circulatory failure and deepening coma. Death may occur from respiratory failure.

	~~'''~~Treatment of Adverse Effects		===Treatment of Adverse Effects===
			#Constipation can be treated with laxatives such as senna tables and lactulose.
	1. Constipation can be treated with laxatives such as senna tables and lactulose.		#Nausea and vomiting can be alleviated by metoclopramide.
			#Intensive supportive therapy may be required to correct respiratory failure and shock. Naloxone is used for rapid reversal of the severe respiratory depression and coma.
	2. Nausea and vomiting can be alleviated by metoclopramide.

	3. Intensive supportive therapy may be required to correct respiratory failure and shock. Naloxone is used for rapid reversal of the severe respiratory depression and coma.

	Euphoria, nausea and vomiting, respiratory depression, constipation and cough suppression.		Euphoria, nausea and vomiting, respiratory depression, constipation and cough suppression.

Ctol2: /* Safety */

2020-09-30T09:53:37Z

Safety

← Older revision		Revision as of 05:53, 30 September 2020
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	Mental status, blood pressure, respiratory drive, and misuse/overuse.		Mental status, blood pressure, respiratory drive, and misuse/overuse.

	Caution: Toxic psychosis, CNS depression, severe, cor pulmonale		===Caution===
			Toxic psychosis, CNS depression, severe, cor pulmonale

	Tolerance and dependence		Tolerance and dependence

	Contraindication~~: where~~ hepatic and renal impairment may result in toxicity		===Contraindication===
			Where hepatic and renal impairment may result in toxicity

	== FAQ ==		== FAQ ==

Ctol2: /* Drug Management */

2020-09-30T09:53:03Z

Drug Management

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	==Drug Management==		==Drug Management==

	Efficiency: Relief of moderate to severe pain, especially that associated with cancer, myocardial infarction and surgery.		===Efficiency===
			Relief of moderate to severe pain, especially that associated with cancer, myocardial infarction and surgery.

	~~'''~~Contraindication:		===Contraindication===
	*acute respiratory depression and obstructive airways disease		*acute respiratory depression and obstructive airways disease
	*acute alcoholism		*acute alcoholism
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	Withdrawal symptoms include yawning, mydriasis, rhinorrhea, sneezing, muscle tremor, weakness, sweating, nausea vomiting, diarrhoea, bone pain, abdominal and muscle cramps, increases in heart rate, respiratory rate, blood pressure and temperature.		Withdrawal symptoms include yawning, mydriasis, rhinorrhea, sneezing, muscle tremor, weakness, sweating, nausea vomiting, diarrhoea, bone pain, abdominal and muscle cramps, increases in heart rate, respiratory rate, blood pressure and temperature.

	Safety~~: mental~~ status, blood pressure, respiratory drive, and misuse/overuse.		===Safety===
			Mental status, blood pressure, respiratory drive, and misuse/overuse.

	Caution: Toxic psychosis, CNS depression, severe, cor pulmonale		Caution: Toxic psychosis, CNS depression, severe, cor pulmonale

Ctol2 at 09:51, 30 September 2020

2020-09-30T09:51:59Z

← Older revision		Revision as of 05:51, 30 September 2020
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	Subcutaneous or intramuscular: 5 to 10 mg every 4 hours; the dose may be increased according to needs.		Subcutaneous or intramuscular: 5 to 10 mg every 4 hours; the dose may be increased according to needs.

	~~'''~~Administration in children		===Administration in children===

	Doses according to age or body-weight, and adjusted according to response:		Doses according to age or body-weight, and adjusted according to response:

Ctol2 at 09:50, 30 September 2020

2020-09-30T09:50:48Z

← Older revision		Revision as of 05:50, 30 September 2020
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	\|DD		\|DD
	\|}		\|}
			==Mechanism of Action==
	Equivalent doses of opioid analgesics		Equivalent doses of opioid analgesics
	{\| class="wikitable"		{\| class="wikitable"

Ctol2 at 09:50, 30 September 2020

2020-09-30T09:50:28Z

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	[[Category: Drugs]] [[Category: Non-opioid Analgesic]] [[Category: Pain relief]]		[[Category: Drugs]] [[Category: Non-opioid Analgesic]] [[Category: Pain relief]]
	'''Diamorphine''' is a more potent opioid analgesic than morphine. It is used for the relief of severe pain especially in palliative care.		'''Diamorphine''' is a more potent opioid analgesic than [[morphine]]. It is used for the relief of severe pain especially in palliative care.

	{\| class="wikitable"		{\| class="wikitable"

Ctol2 at 09:49, 30 September 2020

2020-09-30T09:49:47Z

← Older revision		Revision as of 05:49, 30 September 2020
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	[[Category: Drugs]] [[Category: Non-opioid Analgesic]] [[Category: Pain relief]]		[[Category: Drugs]] [[Category: Non-opioid Analgesic]] [[Category: Pain relief]]
			'''Diamorphine''' is a more potent opioid analgesic than morphine. It is used for the relief of severe pain especially in palliative care.
	~~== Pronunciation ==~~

	~~==Introduction==~~
	Diamorphine is a more potent ~~'''~~opioid analgesic
	than morphine. It is used for the relief of severe pain especially in palliative care.

	{\| class="wikitable"		{\| class="wikitable"

Helen at 06:25, 30 September 2020

2020-09-30T06:25:14Z

← Older revision		Revision as of 02:25, 30 September 2020
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	Contraindication: where hepatic and renal impairment may result in toxicity		Contraindication: where hepatic and renal impairment may result in toxicity

			== FAQ ==
			=== What should I avoid while taking? ===
			Avoid abrupt withdrawal
			=== What happen if I overdose? ===
			Emergency situation, called 999 immediately
			Antidote: Naloxone
			=== What happen if I miss a dose? ===
			Administered by professionals

Helen: /* Drug Management */

2020-09-30T06:23:31Z

Drug Management

← Older revision		Revision as of 02:23, 30 September 2020
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	Caution: Toxic psychosis, CNS depression, severe, cor pulmonale		Caution: Toxic psychosis, CNS depression, severe, cor pulmonale
	Tolerance and dependence		Tolerance and dependence

	Contraindication: where hepatic and renal impairment may result in toxicity		Contraindication: where hepatic and renal impairment may result in toxicity

Helen: /* Drug Management */

2020-09-30T06:23:18Z

Drug Management

← Older revision		Revision as of 02:23, 30 September 2020
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	Caution: Toxic psychosis, CNS depression, severe, cor pulmonale		Caution: Toxic psychosis, CNS depression, severe, cor pulmonale
	~~'''~~Tolerance and dependence		Tolerance and dependence

	Contraindication: where hepatic and renal impairment may result in toxicity		Contraindication: where hepatic and renal impairment may result in toxicity