Ibuprofen - Revision history

Jim at 02:58, 4 August 2022

2022-08-04T02:58:26Z

← Older revision		Revision as of 22:58, 3 August 2022
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	[[Category: Drugs]] [[Category: Non-opioid Analgesic (NSAID)]]		[[Category: Drugs]] [[Category: Non-opioid Analgesic (NSAID)]] [[Category: test]]
	'''Ibuprofen'''(中文: [[布洛芬]]) is an anti-steroidal anti-inflammatory drug, an NSAID. As an NSAID, indomethacin is an analgesic, anti-inflammatory and antipyretic.		'''Ibuprofen'''(中文: [[布洛芬]]) is an anti-steroidal anti-inflammatory drug, an NSAID. As an NSAID, indomethacin is an analgesic, anti-inflammatory and antipyretic.
	It is used in the management of mild to moderate pain and inflammation in conditions such as dysmenorrhea, migraine, postoperative pain, dental pain, musculoskeletal and joints disorders including ankylosing spondylitis, osteoarthritis and rheumatoid arthritis. Also for soft-tissue disorders such as sprains and strains. It can also reduce fever.		It is used in the management of mild to moderate pain and inflammation in conditions such as dysmenorrhea, migraine, postoperative pain, dental pain, musculoskeletal and joints disorders including ankylosing spondylitis, osteoarthritis and rheumatoid arthritis. Also for soft-tissue disorders such as sprains and strains. It can also reduce fever.

Helen: /* Side Effects */

2020-10-14T03:52:19Z

Side Effects

← Older revision		Revision as of 23:52, 13 October 2020
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	!style="text-align: left"\| Common side effects		!style="text-align: left"\| Common side effects
	\|Heartburn, nausea, dyspepsia, diarrhea, constipation, gastrointestinal ulceration/bleeding, headache, dizziness, rash, salt and fluid retention, and high blood pressure.		\|Heartburn, nausea, dyspepsia, diarrhea, constipation, gastrointestinal ulceration/bleeding, headache, dizziness, rash, salt and fluid retention, and high blood pressure.
			\|}
	It increases the risk of heart attack, stroke, kidney failure and liver failure.		It increases the risk of heart attack, stroke, kidney failure and liver failure.
	\|}
	{\| class="wikitable"		{\| class="wikitable"
	!Asthma		!Asthma

Helen: /* Side Effects */

2020-10-14T03:47:29Z

Side Effects

← Older revision		Revision as of 23:47, 13 October 2020
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	==Side Effects==		==Side Effects==
	NSAIDs in general		NSAIDs in general
	Common side effects ~~include heartburn~~, nausea, dyspepsia, diarrhea, constipation, gastrointestinal ulceration/bleeding, headache, dizziness, rash, salt and fluid retention, and high blood pressure.		{\| class = "wikitable"
			!style="text-align: left"\| Common side effects
			\|Heartburn, nausea, dyspepsia, diarrhea, constipation, gastrointestinal ulceration/bleeding, headache, dizziness, rash, salt and fluid retention, and high blood pressure.

	It increases the risk of heart attack, stroke, kidney failure and liver failure.		It increases the risk of heart attack, stroke, kidney failure and liver failure.
			\|}
	{\| class="wikitable"		{\| class="wikitable"
	!Asthma		!Asthma

Helen: /* Drug Names */

2020-10-14T03:09:56Z

Drug Names

← Older revision		Revision as of 23:09, 13 October 2020
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	!Classification藥物分類		!Classification藥物分類
	\|-		\|-
	\|Ibuprofen ~~Tablet 200 mg~~		\|Ibuprofen Suspension 100mg/5ml
	\|		\|IBUP06
	\|Part 1 Poison		\|Part 1 Poison
	\|-		\|-
	\|Ibuprofen ~~Tablet 400 mg~~		\|Ibuprofen tablet 200mg
	\|		\|IBUP01
	\|Part 1 Poison		\|Part 1 Poison
	\|}		\|}

Helen: /* Side Effects */

2020-10-12T07:57:17Z

Side Effects

← Older revision		Revision as of 03:57, 12 October 2020
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	==Side Effects==		==Side Effects==
			NSAIDs in general
	~~===~~NSAIDs in general~~===~~
	Common side effects include heartburn, nausea, dyspepsia, diarrhea, constipation, gastrointestinal ulceration/bleeding, headache, dizziness, rash, salt and fluid retention, and high blood pressure.		Common side effects include heartburn, nausea, dyspepsia, diarrhea, constipation, gastrointestinal ulceration/bleeding, headache, dizziness, rash, salt and fluid retention, and high blood pressure.

	It increases the risk of heart attack, stroke, kidney failure and liver failure.		It increases the risk of heart attack, stroke, kidney failure and liver failure.
			{\| class="wikitable"
	~~Ibuprofen can also worsen asthma.~~		!Asthma
			\|Can be worsened
	~~===~~Cardiovascular risk~~===~~		\|-
	Chronic ibuprofen use has been found correlated with risk of progression to hypertension and myocardial infarction (heart attack). Both the U.S. Food and Drug Administration (FDA) and The European Medicines Agency (EMA) issues warnings of increased heart attack and stroke risk ~~in 2015~~.		!Cardiovascular risk
			\|Chronic ibuprofen use has been found correlated with risk of progression to hypertension and myocardial infarction (heart attack). Both the U.S. Food and Drug Administration (FDA) and The European Medicines Agency (EMA) issues warnings of increased heart attack and stroke risk.
	~~===~~Skin~~===~~		\|-
	~~Along with other~~ NSAIDs~~, ibuprofen has~~ been associated with the onset of bullous pemphigoid.		!Skin
			\|NSAIDs have been associated with the onset of bullous pemphigoid. It can also cause serious skin adverse events such as exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, which can be fatal.
			\|}

	==Pharmacokinetics==		==Pharmacokinetics==

Helen: /* Dosage */

2020-10-12T07:53:41Z

Dosage

← Older revision		Revision as of 03:53, 12 October 2020
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	==Dosage==		==Dosage==
	~~Usual dose for painful conditions:~~
	{\| class="wikitable"		{\| class="wikitable"
	!Pain		!Pain relief
	\|Oral : 400 to 600 mg every 4 to 6 hours to a maximum of 2.4 g daily		\|Oral : 400 to 600 mg every 4 to 6 hours to a maximum of 2.4 g daily

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	Can be applied as a 5% cream, foam, gel or spray solution		Can be applied as a 5% cream, foam, gel or spray solution
	\|-		\|-
	!Fever		!Fever relief
	\|Oral : 200 to 400 mg every 4 to 6 hours to a maximum of 1.2 g daily		\|Oral : 200 to 400 mg every 4 to 6 hours to a maximum of 1.2 g daily
	\|}		\|}

Helen at 07:52, 12 October 2020

2020-10-12T07:52:53Z

← Older revision		Revision as of 03:52, 12 October 2020
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	==Dosage==		==Dosage==
			Usual dose for painful conditions:
			{\| class="wikitable"
			!Pain
			\|Oral : 400 to 600 mg every 4 to 6 hours to a maximum of 2.4 g daily

	~~Usual oral dose for painful conditions~~:		Intravenous infusion :
			400 to 800 mg every 6 hours as necessary

	~~Oral: 400 to 600 mg every 4 to 6 hours to a maximum of 2.4 g daily.~~		Topical
			Can be applied as a 5% cream, foam, gel or spray solution
	~~Intravenous infusion: 400 to 800 mg every 6 hours as necessary.~~		\|-
			!Fever
	~~Topical:~~ applied as a 5% cream, foam, gel or spray solution.		\|Oral : 200 to 400 mg every 4 to 6 hours to a maximum of 1.2 g daily
			\|}
	~~The recommended dose for fever reduction:~~

	Oral: 200 to 400 mg every 4 to 6 hours to a maximum of 1.2 g daily.

	===Administration in children===		===Administration in children===
	Given according to age for the treatment of pain, inflammation of soft-tissue injuries or fever in children:		Given according to age for the treatment of pain, inflammation of soft-tissue injuries or fever in children:
	*1 to 2 months: 5 mg/kg 3 or 4 times daily		{\| class="wikitable"
	*3 to 5 months: 50 mg 3 times daily		\|style="text-align: left"\| 1 to 2 months
	*6 to 11 months: 50 mg 3 ~~or 4~~ times daily		\|Oral : 5 mg/kg 3 or 4 times daily
	*1 to 3 years: 100 mg 3 times daily		\|-
	*4 to 6 years: 150 mg 3 times daily		\|style="text-align: left"\|3 to 5 months
	*7 to 9 years: 200 mg 3 times daily		\|Oral : 50 mg 3 or 4 times daily
	*10 to 11 years: 300 mg 3 times daily		\|-
	*12 to 17 years: initially 300 to 400 mg 3 or 4 times daily, if necessary, to a maximum of 2.4 g daily.		\|style="text-align: left"\| 6 to 11 months
	*For more severe symptoms in children aged between 3 months and 11 years, a dose of 30 mg/kg (maximum 2.4 g) daily in 3 or divided doses may be given.		\|Oral : 100 mg 3 times daily
			\|-
			\|style="text-align: left"\|1 to 3 years
			\|Oral : 100 mg 3 times daily
			\|-
			\|4 to 6 years
			\|Oral : 150 mg 3 times daily
			\|-
			\|7 to 9 years
			\|200 mg 3 times daily
			\|-
			\|10 to 11 years
			\|300 mg 3 times daily
			\|-
			\|12 to 17 years
			\|initially 300 to 400 mg 3 or 4 times daily, if necessary, to a maximum of 2.4 g daily.

			\|}
			For more severe symptoms in children aged between 3 months and 11 years, a dose of 30 mg/kg (maximum 2.4 g) daily in 3 or divided doses may be given.

	==Side Effects==		==Side Effects==

Helen at 08:21, 9 October 2020

2020-10-09T08:21:03Z

← Older revision		Revision as of 04:21, 9 October 2020
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	[[Category: Drugs]] [[Category: Non-opioid Analgesic (NSAID)]]		[[Category: Drugs]] [[Category: Non-opioid Analgesic (NSAID)]]
	'''Ibuprofen''' is an anti-steroidal anti-inflammatory drug, an NSAID. As an NSAID, indomethacin is an analgesic, anti-inflammatory and antipyretic.		'''Ibuprofen'''(中文: [[布洛芬]]) is an anti-steroidal anti-inflammatory drug, an NSAID. As an NSAID, indomethacin is an analgesic, anti-inflammatory and antipyretic.
	It is used in the management of mild to moderate pain and inflammation in conditions such as dysmenorrhea, migraine, postoperative pain, dental pain, musculoskeletal and joints disorders including ankylosing spondylitis, osteoarthritis and rheumatoid arthritis. Also for soft-tissue disorders such as sprains and strains. It can also reduce fever.		It is used in the management of mild to moderate pain and inflammation in conditions such as dysmenorrhea, migraine, postoperative pain, dental pain, musculoskeletal and joints disorders including ankylosing spondylitis, osteoarthritis and rheumatoid arthritis. Also for soft-tissue disorders such as sprains and strains. It can also reduce fever.

			==Drug Names==
	{\| class="wikitable"		{\| class="wikitable"
	!Generic Name 藥名		!Generic Name 藥名

Ctol2: /* Drug Management */

2020-09-30T09:05:43Z

Drug Management

← Older revision		Revision as of 05:05, 30 September 2020
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	==Drug Management==		==Drug Management==

	Efficiency: Pain and inflammation control		===Efficiency===
			Pain and inflammation control

	Safety~~: monitor~~ signs of bleeding and bruising, and blood pressure.		===Safety===
			Monitor signs of bleeding and bruising, and blood pressure.

	===Drug Interaction===		===Drug Interaction===

Ctol2 at 09:00, 30 September 2020

2020-09-30T09:00:23Z

← Older revision		Revision as of 05:00, 30 September 2020
Line 1:		Line 1:
	[[Category: Drugs]] [[Category: Non-opioid Analgesic (NSAID)]]		[[Category: Drugs]] [[Category: Non-opioid Analgesic (NSAID)]]
			'''Ibuprofen''' is an anti-steroidal anti-inflammatory drug, an NSAID. As an NSAID, indomethacin is an analgesic, anti-inflammatory and antipyretic.
	~~==Introduction==~~		It is used in the management of mild to moderate pain and inflammation in conditions such as dysmenorrhea, migraine, postoperative pain, dental pain, musculoskeletal and joints disorders including ankylosing spondylitis, osteoarthritis and rheumatoid arthritis. Also for soft-tissue disorders such as sprains and strains. It can also reduce fever.
	Ibuprofen is an anti-steroidal ~~antiinflammatory~~ drug, an NSAID. As an NSAID, indomethacin is an analgesic, anti-inflammatory and antipyretic.
	It is used in the management of mild to ~~modreate~~ pain and inflammation in conditions such as ~~dysmenoorhoea~~, migraine, postoperative pain, dental pain, musculoskeletal and joints disorders including ankylosing spondylitis, osteoarthritis and rheumatoid arthritis. Also for soft-tissue disorders such as sprains and strains. It can also reduce fever.

	{\| class="wikitable"		{\| class="wikitable"
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	Oral: 200 to 400 mg every 4 to 6 hours to a maximum of 1.2 g daily.		Oral: 200 to 400 mg every 4 to 6 hours to a maximum of 1.2 g daily.

	~~'''~~Administration in children		===Administration in children===
	Given according to age for the treatment of pain, inflammation of soft-tissue injuries or fever in children:		Given according to age for the treatment of pain, inflammation of soft-tissue injuries or fever in children:
	*1 to 2 months: 5 mg/kg 3 or 4 times daily		*1 to 2 months: 5 mg/kg 3 or 4 times daily
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	==Side Effects==		==Side Effects==

	~~As for~~ NSAIDs in general.		===NSAIDs in general===
			Common side effects include heartburn, nausea, dyspepsia, diarrhea, constipation, gastrointestinal ulceration/bleeding, headache, dizziness, rash, salt and fluid retention, and high blood pressure.
	Common side effects include heartburn, nausea, dyspepsia, ~~diarrhoea~~, constipation, gastrointestinal ulceration/bleeding, headache, dizziness, rash, salt and fluid retention, and high blood pressure.

	It increases the risk of heart attack, stroke, kidney failure and liver failure.		It increases the risk of heart attack, stroke, kidney failure and liver failure.
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	Ibuprofen can also worsen asthma.		Ibuprofen can also worsen asthma.

	~~'''~~Cardiovascular risk		===Cardiovascular risk===

	Chronic ibuprofen use has been found correlated with risk of progression to hypertension and myocardial infarction (heart attack). Both the U.S. Food and Drug Administration (FDA) and The European Medicines Agency (EMA) issues warnings of increased heart attack and stroke risk in 2015.		Chronic ibuprofen use has been found correlated with risk of progression to hypertension and myocardial infarction (heart attack). Both the U.S. Food and Drug Administration (FDA) and The European Medicines Agency (EMA) issues warnings of increased heart attack and stroke risk in 2015.

	~~'''~~Skin		===Skin===

	Along with other NSAIDs, ibuprofen has been associated with the onset of bullous pemphigoid.		Along with other NSAIDs, ibuprofen has been associated with the onset of bullous pemphigoid.

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	Safety: monitor signs of bleeding and bruising, and blood pressure.		Safety: monitor signs of bleeding and bruising, and blood pressure.

	Drug Interaction:		===Drug Interaction===

	Interactions involving NSAIDs include		Interactions involving NSAIDs include
	*enhancement of the effects of oral anticoagulants		*enhancement of the effects of oral anticoagulants
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	*Use of more than one NSAID together (including aspirin) should be avoided because of the increased risk of adverse effects		*Use of more than one NSAID together (including aspirin) should be avoided because of the increased risk of adverse effects
	*The risk of gastrointestinal bleeding and ulceration is increased when used with steroids, the SSRIs, the SNRI venlafaxaine, the antiplatelet clopidogrel, bisphosphonates or pentoxifylline		*The risk of gastrointestinal bleeding and ulceration is increased when used with steroids, the SSRIs, the SNRI venlafaxaine, the antiplatelet clopidogrel, bisphosphonates or pentoxifylline
			*Co-administration of ACE inhibitor can increase risk of kidney problem and increase hypotensive effect.
			*Aspirin.

	~~Co-adminstration of~~		===Caution===
	~~ACE inhibitor can increase risk of kidney problem and increase hypotensive effect.~~
	~~Asprin.~~

	Caution:

	*Allergic reaction,		*Allergic reaction,
	*Previous peptic ~~ucler~~		*Previous peptic ulcer
	*uncontrolled hypertension,		*uncontrolled hypertension,
	*Impaired renal function		*Impaired renal function

	Contraindication:		===Contraindication===

	*Active peptic ulcer		*Active peptic ulcer
	*patient with severe renal impairment.		*patient with severe renal impairment.