Perindopril - Revision history

Zeki at 07:16, 9 September 2024

2024-09-09T07:16:09Z

← Older revision		Revision as of 03:16, 9 September 2024
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	'''Drug class: [[:Category: ACE inhibitors \| Angiotensin Converting Enzyme Inhibitors, ACEI]]		'''Drug class: [[:Category: ACE inhibitors \| Angiotensin Converting Enzyme Inhibitors, ACEI]]

	'''Perindopril (ACERTIL)''' ~~(中文：~~[[培哚普利]])		'''Perindopril (ACERTIL)'''（中文：[[培哚普利]]）

	==Pronunciation==		==Pronunciation==

Zeki at 02:49, 5 September 2024

2024-09-05T02:49:45Z

← Older revision		Revision as of 22:49, 4 September 2024
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	'''Drug class: [[:Category: ACE inhibitors \| Angiotensin Converting Enzyme Inhibitors, ACEI]]		'''Drug class: [[:Category: ACE inhibitors \| Angiotensin Converting Enzyme Inhibitors, ACEI]]

	'''Perindopril''' (中文：[[培哚普利]])		'''Perindopril (ACERTIL)''' (中文：[[培哚普利]])

	==Pronunciation==		==Pronunciation==

Zeki at 01:46, 5 September 2024

2024-09-05T01:46:11Z

← Older revision		Revision as of 21:46, 4 September 2024
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	'''Drug class: [[:Category: ACE inhibitors \| Angiotensin Converting Enzyme Inhibitors, ACEI]]		'''Drug class: [[:Category: ACE inhibitors \| Angiotensin Converting Enzyme Inhibitors, ACEI]]

	'''Perindopril''' (~~中文:~~ [[培哚普利]])		'''Perindopril''' (中文：[[培哚普利]])

	==Pronunciation==		==Pronunciation==

Zeki at 01:45, 5 September 2024

2024-09-05T01:45:42Z

← Older revision		Revision as of 21:45, 4 September 2024
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	[[Category: Drugs]][[Category: ACE inhibitors]]		[[Category: Drugs]][[Category: ACE inhibitors]]

			[[:Category: Cardiovascular Drug \| '''Cardiovascular Drug''']]

			'''Drug class: [[:Category: ACE inhibitors \| Angiotensin Converting Enzyme Inhibitors, ACEI]]

	'''Perindopril''' (中文: [[培哚普利]])		'''Perindopril''' (中文: [[培哚普利]])

Helen: /* Drug Management */

2024-06-21T02:01:23Z

Drug Management

← Older revision		Revision as of 22:01, 20 June 2024
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	==Drug Management==		==Drug Management==
	'''Safety		'''Safety

	Your very first dose may make you feel dizzy, so it is best to take it at bedtime. After the first dose, if you do not feel dizzy, you can take perindopril in the morning.		Your very first dose may make you feel dizzy, so it is best to take it at bedtime. After the first dose, if you do not feel dizzy, you can take perindopril in the morning.

Zeki at 07:38, 14 June 2024

2024-06-14T07:38:37Z

Show changes

Zeki at 07:15, 14 June 2024

2024-06-14T07:15:43Z

← Older revision		Revision as of 03:15, 14 June 2024
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	[[Category: Drugs]][[Category: ACE inhibitors]]		[[Category: Drugs]][[Category: ACE inhibitors]]

	'''Perindopril''' ([[培哚普利]]) ~~is an Angiotensin Converting Enzyme Inhibitor (ACEI).~~		'''Perindopril''' (中文: [[培哚普利]])

	==Pronunciation==		==Pronunciation==
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	[[File:Perindopril 4mg (ACERTIL 4mg).mp3]]		[[File:Perindopril 4mg (ACERTIL 4mg).mp3]]

	~~{\| class~~=~~"wikitable"~~		==Common Strengths of Perindopril==
	~~!style~~=~~"text-align: left"\| Generic Name:~~		Perindopril is available in the following strengths:
	\|Perindopril		*2 mg
	\|-		*4 mg
	~~!style~~=~~"text-align: left"\| Class:~~		*5 mg
	~~\|Cardiovascular Drug~~		*10 mg
	\|-
	~~!style="text-align: left"\| Subclass~~:
	~~\|ACE inhibitor~~
	\|-
	~~!style="text-align: left"\| HK Legal Classification:~~
	~~\|P1S1S3~~
	\|}

	==Drug Names==		==Drug Trade Names of Perindopril==
	~~{\| class="wikitable"~~		The brand names for prindopril include:
	~~!Generic Name 藥物化學名稱~~		*Acertil
	~~!HA Code 藥物代碼~~		*Acertil AR
	~~!HK Legal Classification香港法律藥物分類~~		*Acertil Plus
	~~!Brand Name 品牌名稱~~
	\|-
	~~\| Perindopril Tertbutylamine Tab 2mg~~
	~~\| PERI28~~
	~~\| P1S1S3~~
	~~\| rowspan="4" \| ACERTIL~~ AR ~~Tablet 5mg~~
	~~ACERTIL AR Tablet 10mg~~

	~~ACERTIL PLUS TAB 2.5mg/0.625mg~~ (~~perindopril arginine 5 mg, indapamide 0~~.~~625mg)~~		==Mechanism of Action==
			Perindopril is an inhibitor of Angiotensin Converting Enzyme (ACE inhibitor).

	~~ACERTIL PLUS TAB 5MG/1.25MG~~ (~~perindopril arginine 5 mg, indapamide 1~~.~~25mg)~~		The beneficial effects of ACE inhibitors appear to result primarily from the suppression of the plasma renin-angiotensin-aldosterone (RAA) system.

	~~ACERTIL PLUS TAB 10mg/2~~.~~5mg~~ (~~perindopril arginine 10 mg, indapamide 2.5mg~~)		Renin is an enzyme synthesized by the kidneys and released into the circulation where it converts angiotensinogen to angiotensin-I. Angiotensin-I is then converted by angiotensin converting enzyme (ACE) to angiotensin-II. Angiotensin-II is a potent vasoconstrictor responsible for arterial vasoconstriction and increased blood pressure as well as for stimulation of the adrenal gland to secrete aldosterone.
	\|-
	~~\| Perindopril Tertbutylamine Tab 4mg~~
	~~\| PERI17~~
	~~\| P1S1S3~~
	\|-
	~~\| Perindopril Arginine Tab 5mg~~
	~~\| PERI29~~
	~~\| P1S1S3~~
	\|-
	~~\| Perindopril Arginine Tab 10mg~~
	\|
	\|
	\|}

	~~==Mechanism of Action ==~~
	~~The beneficial effects of ACE inhibitors appear to result primarily from the suppression of the plasma renin-angiotensin-aldosterone (RAA) system.~~
	Renin is an enzyme synthesized by the kidneys and released into the circulation where it converts angiotensinogen to angiotensin-I. Angiotensin-I is then converted by angiotensin converting enzyme (ACE) to angiotensin-II. Angiotensin-II is a potent vasoconstrictor responsible for arterial vasoconstriction and increased blood pressure as well as for stimulation of the adrenal gland to secrete aldosterone.
	Inhibition of ACE results in decreased plasma angiotensin-II level, which leads to decreased vasopressor activity and to reduced aldosterone secretion. The latter decrease results in an increase in serum potassium concentration.		Inhibition of ACE results in decreased plasma angiotensin-II level, which leads to decreased vasopressor activity and to reduced aldosterone secretion. The latter decrease results in an increase in serum potassium concentration.

	Perindopril is used in the treatment of hypertension and heart failure. Perindopril helps to reduce the risk of future strokes and heart attacks. It also improves your survival if you are taking it following a heart attack or heart surgery.		Perindopril is used in the treatment of hypertension and heart failure. Perindopril helps to reduce the risk of future strokes and heart attacks. It also improves your survival if you are taking it following a heart attack or heart surgery.

	It works by widening your blood vessels and making it easier for your heart to pump blood around your body. This can improve the symptoms of heart failure.		It works by widening your blood vessels and making it easier for your heart to pump blood around your body. This can improve the symptoms of heart failure.

	Perindopril can be used alone or in combination with other antihypertensive agents such as indapamide.		Perindopril can be used alone or in combination with other antihypertensive agents such as indapamide.

	== Route of Administration ==		==Route of Administration==
	Perindopril is administered orally in a single daily dose		Perindopril is administered orally in a single daily dose

	==~~Dosage~~==		==Dosages==
	~~'''~~Dose for ~~perindopril~~ Tertbutylamine		*Dose for Perindopril Tertbutylamine
			**Hypertension: 4 mg once a day (the maximum dose is 8 mg once daily)
	*Hypertension ~~- 4mg~~ once a day (the maximum dose is 8 mg once daily)		**Heart failure: 4 mg once a day
	*Heart failure ~~– 4mg~~ once a day		**After a heart attack: 8 mg once a day
	*After a heart attack ~~– 8mg once a day~~

	~~'''Dose for perindopril Arginine~~
	*Hypertension - 5mg once a day (the maximum dose is 10 mg ~~once daily)~~
	*Heart failure – 5mg once a day
	*After a heart attack – 10mg once a day

	~~<u>When will I feel better?</u>~~

	Perindopril ~~starts to work within~~ a ~~few hours to reduce high blood pressure, but it may take up to~~ a ~~month to achieve its full effects.~~		*Dose for Perindopril Arginine
			**Hypertension: 5 mg once a day (the maximum dose is 10 mg once daily)
			**Heart failure: 5 mg once a day
			**After a heart attack: 10 mg once a day

	If you are taking perindopril for heart failure, it may take weeks, even months, before you feel better.		'''When will I feel better?
			*Perindopril starts to work within a few hours to reduce high blood pressure, but it may take up to a month to achieve its full effects.
			*If you are taking perindopril for heart failure, it may take weeks, even months, before you feel better.

	==Side Effects==		==Side Effects==

Helen: /* Side Effects */

2022-10-28T03:52:34Z

Side Effects

← Older revision		Revision as of 23:52, 27 October 2022
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	\|Very rare		\|Very rare
	\|Glossitis, pancreatitis		\|Glossitis, pancreatitis
	\|-
	\|		\|
	\|-		\|-

Helen: /* Side Effects */

2022-10-28T03:52:13Z

Side Effects

← Older revision		Revision as of 23:52, 27 October 2022
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	\|Oedema of the face, extremities, lips, tongue, glottis, and/or larynx		\|Oedema of the face, extremities, lips, tongue, glottis, and/or larynx
	\|-		\|-
	\| rowspan="4" \| '''Gastro-intestinal disorders		\| rowspan="3" \| '''Gastro-intestinal disorders
	\|Common		\|Common
	\|Nausea, vomiting, diarrhoea, abdominal pain, dyspepsia, constipation		\|Nausea, vomiting, diarrhoea, abdominal pain, dyspepsia, constipation

Helen: /* Side Effects */

2022-10-28T03:44:26Z

Side Effects

← Older revision		Revision as of 23:44, 27 October 2022
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	\|Glossitis, pancreatitis		\|Glossitis, pancreatitis
	\|-		\|-
	~~{clear}~~		\|
	\|-		\|-
	\|'''Cardiac disorders		\|'''Cardiac disorders