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| '''Anticoagulants'''（中文：[[:Category: 抗凝血藥 | 抗凝血藥]]）
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| Anticoagulants are used in the treatment and prophylaxis of thromboembolic disorders.
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| '''Direct anticoagulants
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| Rivaroxaban, apixaban, and edoxaban are orally active factor Xa inhibitors.
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| The direct thrombin inhibitors bind to the active thrombin site and inhibit both free and clot-bound thrombin. Dabigatran, given orally as the prodrug dabigatran etexilate, is used in the prophylaxis of venous thromboembolism.
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| '''Indirect anticoagulants
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| Indirect anticoagulants act by depressing the hepatic vitamin K-dependent synthesis of coagulation factors II (prothrombin), VII, IX, and X, and of the anticoagulant protein C and its cofactor protein S. Warfarin, a coumarin, is the main drug used.
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Latest revision as of 23:16, 7 July 2024
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