Irbesartan

Irbesartan (中文:厄貝沙坦) is an angiotensin receptor blocker. 

Pronunciation

Irbesartan 150mg (APROVEL 150mg)

Generic Name:	Irbesartan
Class:	Cardiovascular Drug
Subclass:	angiotensin receptor blocker
Legal Classification:	P1S1S3

Drug Names

Generic Name 藥物化學名稱	HA Code 藥物代碼	Legal Classification法律藥物分類	Brand Name 藥名
Irbesartan Tablet 150mg	IRBE01	P1S1S3	APROVEL TABLET C0APROVEL TAB 150/12.5MG (irbesartan 150mg + hydrochlorothiazide 12.5mg) C0APROVEL TAB 300/12.5MG (irbesartan 300mg + hydrochlorothiazide 12.5mg)
Irbesartan Tablet 300mg	IRBE02	P1S1S3

Mechanism of Action

Irbesartan relaxes and widens your blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. It is used to treat high blood pressure and heart failure. It helps to prevent future strokes, heart attacks and diabetic kidney disease. If you have diabetic kidney disease, it helps to protect your kidneys and slows down the disease. It reduces high blood pressure and the amount of protein you lose through your kidneys.

Route of Administration

Irbesartan is given orally as tablets. After a dose the hypotensive effect peaks within 3 to 6 hours and persists for at least 24 hours. The maximum hypotensive effect is achieved within 4 to 6 weeks after starting therapy.

Dosage

The dose of irbesartan depends on why you need the medicine.

The usual dose for both high blood pressure and diabetic kidney disease is 150mg to 300mg, taken once a day.

If you are over 75, or you have liver or kidney problems, your dose may be lower. Initially 75mg – 150mg once a day.