Metoprolol Tartrate: Difference between revisions

From SEHK Wiki
← Older editNewer edit →
Helen (talk | contribs)
2,599 edits
No edit summary
Helen (talk | contribs)
2,599 edits
No edit summary
Line 3: Line 3:
===Metoprolol tartrate 100mg===
===Metoprolol tartrate 100mg===
[[File:Metoprolol tartrate 100mg.mp3]]
[[File:Metoprolol tartrate 100mg.mp3]]
===Metoprolol tartrate 75mg===


===Metoprolol tartrate 50mg===
===Metoprolol tartrate 50mg===
[[File:Metoprolol tartrate 50mg.mp3]]
[[File:Metoprolol tartrate 50mg.mp3]]
===Metoprolol tartrate 37.5mg===
===Metoprolol tartrate 25mg===
===Metoprolol succinate 200mg===
===Metoprolol succinate 100mg===
===Metoprolol succinate 50mg===
===Metoprolol succinate 25mg===


{| class="wikitable"
{| class="wikitable"
!style="text-align: left"| Generic Name:
!style="text-align: left" | Generic Name:
|Metoprolol Tartrate
|Metoprolol Tartrate, Metoprolol succinate
|-
|-
!style="text-align: left"| Class:
!style="text-align: left"| Class:
Line 21: Line 35:
|}
|}


==Common Strengths of Metoprolol==
==Drug Name==
Metoprolol is available in the following strengths:
{| class="wikitable"
!Generic Name 藥物化學名稱
!HA Code 藥物代碼
!Legal Classification 法律藥物分類
!Brand Name
|-
| Metoprolol Tartrate Tablet 25mg
|
|
| rowspan="5" | LOPRESSOR
|-
| Metoprolol Tartrate Tablet 37.5mg
|
|
|-
| Metoprolol Tartrate Tablet 50mg
| METO07
|
|-
| Metoprolol Tartrate Tablet 75mg
|
|
|-
| Metoprolol Tartrate Tablet 100mg
| METO06
|
|-
| Metoprolol Succinate Tablet 25mg
| METO16
|
| rowspan="4" | BETALOC ZOK
|-
| Metoprolol Succinate Tablet 50mg
| METO13
|
|-
| Metoprolol Succinate Tablet 100mg
| METO10
|
|-
| Metoprolol Succinate Tablet 200mg
| METO11
|
|}
 
==Mechanism of Action==
Metoprolol is a β1-selective (cardio-selective) beta-blocker. It works by blocking the action of epinephrine (adrenaline) on beta-1 receptors in the heart. This slows the heart rate, reduces force of heart contractions, oxygen demand and decreases blood pressure.


- Immediate-release tablets (metoprolol tartrate): 25mg, 37.5mg, 50mg, 75mg, 100mg <ref>https://www.medicalnewstoday.com/articles/metoprolol-oral-tablet</ref>
==Route of Administration==
Metoprolol is available for:
*Oral administration as immediate-release and extended-release tablets
*Intravenous injection (given by healthcare providers)


- Extended-release tablets (metoprolol succinate): 25mg, 50mg, 100mg, 200mg
==Dosages==
*Hypertension
**Immediate-release: Typical starting 50 mg once daily, up to 400 mg/day maximum
**Extended-release: Typical starting 100 mg once daily, up to 400 mg/day maximum
*Heart failure: dosage not specified
**Immediate-release: Typical 25-100 mg twice daily
**Extended-release: Typical 25-200 mg once daily
*Diabetic kidney disease: Dosage not specified, adjust based on patient respnose.


==Side Effects==
==Side Effects==
Line 42: Line 112:


{| class="wikitable"
{| class="wikitable"
!style="text-align: left"| Frequency
!style="text-align: left"| System Organ Class
!Frequency
!Adverse reactions
!Adverse reactions
|-
|-
|Very common
| rowspan="3" | '''Nervous system disorders
|Bradycardia
| Common
|-
|Dizzinss, Fatigue, Memory problem
| rowspan="4" | Common
|Dizziness
|-
|Fatigue
|-
|memory problems
|-
|Diarrhea
|-
| rowspan="4" |Uncommon
|Depression
|-
|-
|Confusion
| Uncommon
| Depression, Confusion, Insomnia
|-
|-
|Insomnia
| Rare
| Nightmares
|-
|-
|Rash
| '''Skin disorders
| Uncommon
| Rash
|-
|-
|Rare
| '''Gastro-intestinal disorders
|Nightmare
| Common
| Diarrhoea
|}
|}
==Pharmacokinetics==
*Well absorbed from GI tract
*Extensively metabolized in liver
*Elimination half-life 6-7 hours
*Excreted in urine


==Notes==
==Notes==
<references />
<references />

Revision as of 00:09, 7 June 2024

Pronunciation

Metoprolol tartrate 100mg

Metoprolol tartrate 75mg

Metoprolol tartrate 50mg

Metoprolol tartrate 37.5mg

Metoprolol tartrate 25mg

Metoprolol succinate 200mg

Metoprolol succinate 100mg

Metoprolol succinate 50mg

Metoprolol succinate 25mg

Generic Name: Metoprolol Tartrate, Metoprolol succinate
Class: Cardiovascular Drug
Subclass: Beta blocker
Legal Classification:

Drug Name

Generic Name 藥物化學名稱 HA Code 藥物代碼 Legal Classification 法律藥物分類 Brand Name
Metoprolol Tartrate Tablet 25mg LOPRESSOR
Metoprolol Tartrate Tablet 37.5mg
Metoprolol Tartrate Tablet 50mg METO07
Metoprolol Tartrate Tablet 75mg
Metoprolol Tartrate Tablet 100mg METO06
Metoprolol Succinate Tablet 25mg METO16 BETALOC ZOK
Metoprolol Succinate Tablet 50mg METO13
Metoprolol Succinate Tablet 100mg METO10
Metoprolol Succinate Tablet 200mg METO11

Mechanism of Action

Metoprolol is a β1-selective (cardio-selective) beta-blocker. It works by blocking the action of epinephrine (adrenaline) on beta-1 receptors in the heart. This slows the heart rate, reduces force of heart contractions, oxygen demand and decreases blood pressure.

Route of Administration

Metoprolol is available for:

  • Oral administration as immediate-release and extended-release tablets
  • Intravenous injection (given by healthcare providers)

Dosages

  • Hypertension
    • Immediate-release: Typical starting 50 mg once daily, up to 400 mg/day maximum
    • Extended-release: Typical starting 100 mg once daily, up to 400 mg/day maximum
  • Heart failure: dosage not specified
    • Immediate-release: Typical 25-100 mg twice daily
    • Extended-release: Typical 25-200 mg once daily
  • Diabetic kidney disease: Dosage not specified, adjust based on patient respnose.

Side Effects

The following definitions of frequencies are used:

Very common ≥ 1/10

Common ≥ 1/100 to < 1/10

Uncommon ≥1/1,000 to <1/100

Rare ≥ 1/10,000 to < 1/1,000

Very rare < 1/10,000

System Organ Class Frequency Adverse reactions
Nervous system disorders Common Dizzinss, Fatigue, Memory problem
Uncommon Depression, Confusion, Insomnia
Rare Nightmares
Skin disorders Uncommon Rash
Gastro-intestinal disorders Common Diarrhoea

Pharmacokinetics

  • Well absorbed from GI tract
  • Extensively metabolized in liver
  • Elimination half-life 6-7 hours
  • Excreted in urine

Notes

Retrieved from "https://www.sehk-wiki.org/index.php?title=Metoprolol_Tartrate&oldid=3429"