Betamethasone: Difference between revisions
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[[Category: Drugs]] [[Category:Immunosuppression agent, Immunosuppression agent, | [[Category: Drugs]] [[Category:Immunosuppression agent, Immunosuppression agent, | ||
Steroid replacement agent | Steroid replacement agent ]] | ||
==Introduction= | |||
Betamethasone is a steroid with anti-inflammatory and immunosuppressant effects. It is used to treat a wide range of inflammatory and autoimmune conditions. | |||
Indications include: | |||
*Inflammatory bowel disease | |||
*Asthma | |||
*Croup in children | |||
*dermatitis | |||
*Rheumatoid arthritis | |||
{| class = "wikitable" | |||
!style="text-align: left"| Equivalent anti-inflammatory doses of steroids | |||
|- | |||
!style="text-align: left"| Prednisolone 5 mg is equivalent to | |||
|Peak plasma levels in about one hour after ingestion. Absorption from transdermal patches is slow and peak plasma concentrations are reached in 10 to 16 hours after applying the first patch; with subsequent patches, peak concentrations are reached in about 8 hours. | |||
|- | |||
!style="text-align: left"| Metabolism | |||
|Primarily metabolized through hydrolysis. Minimal metabolism occurs via the cytochrome P450. | |||
|- | |||
!style="text-align: left"| Elimination half-life | |||
|1.5 hours after oral doses and about 3 hours after patch removal. | |||
|} | |||
Revision as of 23:06, 4 October 2020
[[Category:Immunosuppression agent, Immunosuppression agent,
Steroid replacement agent ]]
=Introduction
Betamethasone is a steroid with anti-inflammatory and immunosuppressant effects. It is used to treat a wide range of inflammatory and autoimmune conditions.
Indications include:
- Inflammatory bowel disease
- Asthma
- Croup in children
- dermatitis
- Rheumatoid arthritis
| Equivalent anti-inflammatory doses of steroids | |
|---|---|
| Prednisolone 5 mg is equivalent to | Peak plasma levels in about one hour after ingestion. Absorption from transdermal patches is slow and peak plasma concentrations are reached in 10 to 16 hours after applying the first patch; with subsequent patches, peak concentrations are reached in about 8 hours. |
| Metabolism | Primarily metabolized through hydrolysis. Minimal metabolism occurs via the cytochrome P450. |
| Elimination half-life | 1.5 hours after oral doses and about 3 hours after patch removal. |
