Hydrocortisone: Difference between revisions
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*Rheumatoid arthritis | *Rheumatoid arthritis | ||
*Treatment of choice for adrenocortical insufficiency | *Treatment of choice for adrenocortical insufficiency | ||
Hydrocortisone can be given by mouth, topically, or by injection. | Hydrocortisone can be given by mouth, topically, or by injection. | ||
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==Mechanism of Action== | |||
Immunosuppression agent, | |||
Steroid replacement agent, | |||
Anti-inflammatory agent | |||
{| class="wikitable" | |||
!Generic Name | |||
藥名 | |||
!HA Code 藥物代碼 | |||
!Classification藥物分類 | |||
|- | |||
|Hydrocortisone Tablet 20mg | |||
|HYDR06 | |||
|P1S1S3 | |||
|} | |||
==Dosage== | |||
Hydrocortisone is used, usually with a more potent mineralocorticoid fludrocortisone, for replacement therapy in adrenocortical insufficiency. | |||
''By Oral'': as replacement therapy, 20-30 mg daily (usually in 2 doses, the larger in the morning and the smaller in the early evening, to mimic the circadian rhythm of the body). | |||
''By intramuscular injection or slow intravenous injection'': 100-500 mg, 3-4 times in 24 hours or as required. | |||
''Child dose'': as replacement therapy in adrenocortical insufficiency, | |||
''By slow intravenous injection | |||
• Up to 1 year: 25 mg | |||
• 1-5 years: 50 mg | |||
• 6-12 years: 100 mg | |||
Revision as of 01:46, 5 October 2020
Pronunciation
Hydrocortisone 20mg
Introduction
Hydrocortisone is a steroid with anti-inflammatory and immunosuppressant effects. Indications include:
- Hypersensitivity reactions e.g. anaphylaxis and angioedema
- Asthma
- Inflammatory bowel disease
- Eczema, psoriasis and other inflammatory skin conditions
- Rheumatoid arthritis
- Treatment of choice for adrenocortical insufficiency
Hydrocortisone can be given by mouth, topically, or by injection.
Equivalent anti-inflammatory doses of steroids
| Prednisolone 5 mg is equivalent to | Betamethasone 750 micrograms |
|---|---|
| dexamethasone 750 micrograms | |
| hydrocortisone 20 mg | |
| methylprednisolone 4 mg | |
| triamcinolone 4 mg |
Mechanism of Action
Immunosuppression agent, Steroid replacement agent, Anti-inflammatory agent
| Generic Name
藥名 |
HA Code 藥物代碼 | Classification藥物分類 |
|---|---|---|
| Hydrocortisone Tablet 20mg | HYDR06 | P1S1S3 |
Dosage
Hydrocortisone is used, usually with a more potent mineralocorticoid fludrocortisone, for replacement therapy in adrenocortical insufficiency.
By Oral: as replacement therapy, 20-30 mg daily (usually in 2 doses, the larger in the morning and the smaller in the early evening, to mimic the circadian rhythm of the body). By intramuscular injection or slow intravenous injection: 100-500 mg, 3-4 times in 24 hours or as required. Child dose: as replacement therapy in adrenocortical insufficiency,
By slow intravenous injection • Up to 1 year: 25 mg • 1-5 years: 50 mg • 6-12 years: 100 mg
