Lamotrigine: Difference between revisions
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'''Bipolar disorder | '''Bipolar disorder | ||
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Revision as of 03:18, 5 October 2020
Gabapentin is an anticonvulsant medication used to treat epilepsy and to delay or prevent the recurrence of depressive episodes in bipolar disorder. Lamotrigine is FDA-approved therapy for the form of epilepsy known as Lennox-Gastaut syndrome. It reduces the frequency of seizures.
Pronunciation
Lamotrigine 50mg
| Generic Name 藥名 | HA Code 藥物代碼 | Classification藥物分類 |
|---|---|---|
| Lamotrigine Tablet 50mg | LAMO01 | P1S1S3 |
Mechanism of Action
Anticonvulsant medication. It inhibits the sodium channels leading to stabilization of neuronal membrane
Dosage
Epilepsy
By mouth as monotherapy: the initial oral dose for use as monotherapy is 25 mg once daily for 2 weeks followed by 50 mg once daily for 2 weeks; thereafter the dose is increased by a maximum of 50 to 100 mg every 1 to 2 weeks to usual maintenance doses of 100 to 200 mg daily in 1-2 divided doses.
As adjunct to therapy but not taking valproate, the dosage regime is as for monotherapy.
In those taking valproate, the initial oral dose of lamotrigine is 25 mg every other day for 2 weeks followed by 25 mg once daily for 2 weeks; thereafter the dose is increased by a maximum of 25 to 50 mg every 1 to 2 weeks to usual maintenance doses of 100 to 200 mg daily in 1-2 divided doses.
Bipolar disorder
Monotherapy without valprate:
