Oxcarbazepine: Difference between revisions
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'''1. Epilepsy ''' | '''1. Epilepsy ''' | ||
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!style="text-align: left"| | !style="text-align: left"| Oral | ||
|initially 300 mg twice daily increased according to response in steps of up to 600 mg daily at weekly intervals; usual dose rage 0.6 – 2.4 g daily in divided doses. | |initially 300 mg twice daily increased according to response in steps of up to 600 mg daily at weekly intervals; usual dose rage 0.6 – 2.4 g daily in divided doses. | ||
|} | |} | ||
Administration in children | Administration in children | ||
{|class="wikitable" | |||
!style="text-align: left"| 6 – 18 years | |||
|8 – 10 mg/kg daily in 2 divided doses increased according to response in steps of up to 10mg/kg daily at weekly intervals, to a maximum dose of 46 mg/kg daily. | |||
Usual maintenance doses in adjunctive therapy around 30mg/kg daily. | |||
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Revision as of 21:35, 5 October 2020
Introduction
Carbamazepine is an anticonvulsant medication used primarily in the treatment of epilepsy. It has been used both alone and as add-on therapy for partial seizures with or without secondary generalization.
| Generic Name 藥名 | HA Code 藥物代碼 | Classification藥物分類 |
|---|---|---|
| P1S1S3 |
Pronunciation
Oxcarbazepine 600mg
Mechanism of Action
Anticonvulsant medication. It is a sodium channel blocker. It binds to sodium channels and suppresses repetitive neuronal firing.
Dosage
1. Epilepsy
| Oral | initially 300 mg twice daily increased according to response in steps of up to 600 mg daily at weekly intervals; usual dose rage 0.6 – 2.4 g daily in divided doses. |
|---|
Administration in children
| 6 – 18 years | 8 – 10 mg/kg daily in 2 divided doses increased according to response in steps of up to 10mg/kg daily at weekly intervals, to a maximum dose of 46 mg/kg daily.
Usual maintenance doses in adjunctive therapy around 30mg/kg daily. |
|---|
