Amlodipine: Difference between revisions
| Line 56: | Line 56: | ||
''Elderly | ''Elderly | ||
Amlodipine used at similar doses in elderly or younger patients. | Amlodipine used at similar doses in elderly or younger patients. | ||
''Hepatic impairment | ''Hepatic impairment | ||
May need dose reduction – half-life prolonged | May need dose reduction – half-life prolonged | ||
Revision as of 21:58, 3 August 2022
Pronunciation
Amlodipine 10mg
Amlodipine 5mg
Pronunciation
Amlodipine 10mg
Amlodipine 5mg
Alprazolam 0.25mg (XANAX)
Drug Names
| Generic Name 藥物化學名稱 | HA Code 藥物代碼 | Legal Classification法律藥物分類 | Brand Name 品牌名稱 |
|---|---|---|---|
| Amlodipine Besylate Tablet 5mg | AMLO01 | P1S1S3 | NORVASC |
| Amlodipine Besylate Tablet 5mg | AMLO02 | P1S1S3 | NORVASC |
Mechanism of Action
Amlodipine relaxes and widens blood vessels. It does this by blocking calcium going into muscles in the heart and blood vessels. Muscles need calcium to contract, so when you block the calcium, it makes the muscle cells relax. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. In angina, amlodipine works by improving the blood and oxygen supply to your heart. Angina is chest pain that comes on when not enough blood gets to the muscles of the heart. This usually happens because the arteries going to the heart become hardened and narrowed.
Route of Administration :
Amlodipine is given orally as the besylate, but doses are expressed in terms of the base. Amlodipine besylate 6.9 mg is equivalent to about 5 mg of amlodipine.
Dosage
Agina
- BY MOUTH
- Adult: initially 5 mg once daily; maximum 10 mg per day
Hypertension
- BY MOUTH
- Adult: initially 5 mg once daily; maximum 10 mg per day
Elderly
Amlodipine used at similar doses in elderly or younger patients.
Hepatic impairment
May need dose reduction – half-life prolonged
