Gabapentin: Difference between revisions
| Line 48: | Line 48: | ||
|} | |} | ||
As with other antiepileptics, withdrawal of gabapentin therapy or transition to or from another type of antiepileptic therapy should be made gradually to avoid precipitating an increase in seizure frequency. | |||
Withdrawal symptoms typically emerge within 12 hours to 7 days after stopping gabapentin. Commonly reported symptoms include agitation, confusion, disorientation, upset stomach and sweating. In some cases, patients experienced delirium and withdrawal seizures, which may only respond to the re-administration of gabapentin. | |||
Revision as of 21:59, 28 September 2020
Catergory: Anticonvulsant medication
Pronunciation
Gabapentin 100mg
Gabapentin 300mg
| Generic Name 藥名 | HA Code 藥物代碼 | Classification藥物分類 |
|---|---|---|
| Gabapentin Capsule 100mg | GABA01 | P1S1S3 |
Dosage
| Epilepsy | By mouth: the initial oral dose is 300 mg on day 1, then 300mg twice daily on day 2, then 300mg 3 times daily on day 3. Alternatively, 300 mg three times daily on day 1; then increased according to response in steps of 300 mg every 2 -3 days.
Usual dose: 0.9 – 3.6 g daily in 3 divided doses (Max. 4.8 g daily) Doses in children, for use as adjunctive therapy in children aged 6 years and over, and as monotherapy in those aged 12 years or over. 6-12 years (adjunctive therapy):
|
|---|---|
| Neuropathic Pain | By mouth:
Alternatively, 300 mg 3 times daily on day 1, then increased according to response in steps of 300mg (in 3 divided doses) every 2-3 days up to max. 3.6 g daily. |
| Migraine prophylaxis | By mouth:
|
As with other antiepileptics, withdrawal of gabapentin therapy or transition to or from another type of antiepileptic therapy should be made gradually to avoid precipitating an increase in seizure frequency. Withdrawal symptoms typically emerge within 12 hours to 7 days after stopping gabapentin. Commonly reported symptoms include agitation, confusion, disorientation, upset stomach and sweating. In some cases, patients experienced delirium and withdrawal seizures, which may only respond to the re-administration of gabapentin.
