Etodolac: Difference between revisions
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'''In the treatment of rheumatoid arthritis and osteoarthritis: | '''In the treatment of rheumatoid arthritis and osteoarthritis: | ||
Oral: initially 600 to 1000 mg daily in divided doses adjusted to response to a maintenance dose of 300 to 600 mg daily. Modified-release preparations are available for once-daily use in stable conditions. | |Oral: initially 600 to 1000 mg daily in divided doses adjusted to response to a maintenance dose of 300 to 600 mg daily. Modified-release preparations are available for once-daily use in stable conditions. | ||
'''For treatment of acute pain: | |'''For treatment of acute pain: | ||
Oral: 200 to 400 mg every 6 to 8 hours, to a maximum of 1 g daily. | |Oral: 200 to 400 mg every 6 to 8 hours, to a maximum of 1 g daily. | ||
Piroxicam has been given in similar doses as a rectal suppository or on a short-term basis by intramuscular injection. Piroxicam is one of the few NSAIDs that can be given parenteral routes. | |Piroxicam has been given in similar doses as a rectal suppository or on a short-term basis by intramuscular injection. Piroxicam is one of the few NSAIDs that can be given parenteral routes. | ||
'''Administration in children | |'''Administration in children | ||
Etodolac has been used in children with juvenile idiopathic arthritis. The following doses, given according to body-weight, are recommended for children aged 6 years and over: | |Etodolac has been used in children with juvenile idiopathic arthritis. The following doses, given according to body-weight, are recommended for children aged 6 years and over: | ||
*20 to 30 kg: 400 mg once daily | *20 to 30 kg: 400 mg once daily | ||
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*46 to 60 kg: 800 mg once daily | *46 to 60 kg: 800 mg once daily | ||
*Over 60 kg: 1 g once daily | *Over 60 kg: 1 g once daily | ||
==Side Effects== | ==Side Effects== | ||
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Revision as of 00:00, 29 September 2020
| Generic Name 藥名 | HA Code 藥物代碼 | Classification藥物分類 |
|---|---|---|
| Etodolac Capsule 200mg | P1S1S3 |
Mechanism of Action
Anti-inflammatory agent, Non-steroidal anti-inflammatory drug (NSAID) selective COX-2 inhibitor
Dosage
In the treatment of rheumatoid arthritis and osteoarthritis:
|Oral: initially 600 to 1000 mg daily in divided doses adjusted to response to a maintenance dose of 300 to 600 mg daily. Modified-release preparations are available for once-daily use in stable conditions.
|For treatment of acute pain:
|Oral: 200 to 400 mg every 6 to 8 hours, to a maximum of 1 g daily.
|Piroxicam has been given in similar doses as a rectal suppository or on a short-term basis by intramuscular injection. Piroxicam is one of the few NSAIDs that can be given parenteral routes.
|Administration in children
|Etodolac has been used in children with juvenile idiopathic arthritis. The following doses, given according to body-weight, are recommended for children aged 6 years and over:
- 20 to 30 kg: 400 mg once daily
- 31 to 45 kg: 600 mg once daily
- 46 to 60 kg: 800 mg once daily
- Over 60 kg: 1 g once daily
Side Effects
|
