Oxycodone

Pronunciation

Generic Name 藥名	HA Code 藥物代碼	Classification藥物分類
Oxycodone Capsule 5mg	OXYC04	DD
Oxycodone PR Tablet 5mg	OXYC06	DD
Oxycodone PR Tablet 10mg	OXYC07	DD

Equivalent doses of opioid analgesics

Analgesic/Route	Dose
Codeine: PO	100 mg
Diamorphine: IM, IV, SC	3 mg
Dihydrocodeine: PO	100 mg
Morphine: PO	10 mg
Morphine: IM, IV, SC	5 mg
Oxycodone: PO	6.6 mg
Tramadol: PO	100 mg

Dosage

Moderate to severe pain:

A usual oral starting dose for opioid-naïve patients in severe pain is 5 mg every 4 to 6 hours increased thereafter as necessary according to response.

For patients who have been receiving a strong opioid analgesic the initial dose of oxycodone should be based on the daily opioid requirement. UK licensed product information suggests that 10 mg of oral oxycodone is equivalent to about 20mg of oral morphine.

Oxycodone hydrochloride may also be given orally as a modified release preparation every 12 hours.

Oral
immediate release formulations : 5mg q4-6h, max 400 mg PRN	modified release formulation: 10mg q12h, max 200 mg q12h PRN
intravenous	1 to 10 mg initially, given over 1 to 2 minutes, and repeated every 4 hours.