Pericyazine

Pericyazine(中文:[[ ]]) is a typical antipsychotic medication. Periciazine is indicated:

1. In adults with schizophrenia or other psychoses, for the treatment of symptoms or prevention of relapse.
2. As a short-term adjuntive management of severe anxiety, and violent or dangerously impulseive behavior.

Periciazine is not recommended for children.

Pronunciation

Pericyazine 10mg

Pericyazine 2.5mg

Drug Names

Generic Name 藥名	HA Code 藥物代碼	Classification藥物分類
Pericyazine Tab 2.5 mg	PERI01	P1S1S3
Pericyazine Tab 10 mg	PERI02	P1S1S3

Mechanism of Action

Pericyazine is presumed to act primarily in the subcortical areas, by blocking central alpha-adrenergic receptors and the D1 dopamine receptor. The presumed effectiveness of antipsychotic drugs relied on their ability to block dopamine receptors. This assumption arose from the dopamine hypothesis that maintains that both schizophrenia and bipolar disorder are a result of excessive dopamine activity.

Dosage

Indication	Dose
Schizophrenia and other psychoses	By mouth ADULT: Initially 75 mg daily in divided doses, Increased at weekly intervals by 25 mg, according to response. Maximum 300 mg per day. ELDERLY or debilitated patients: Initially 15-30 mg daily in divided doses, then Increased at weekly intervals by 25 mg, according to response. Maximum 300 mg per day
Short-term adjunctive management of severe anxiety, and violent or dangerously impulse behaviour	By mouth ADULT: 15-30 mg daily in 2 divided doses ELDERLY or debilitated patients: 5-10 mg 2-3 daily in 2 divided doses