Irbesartan

Irbesartan (中文：厄貝沙坦)

Pronunciation

Irbesartan 150mg (APROVEL 150mg)

Common Strengths of Irbesartan

Irbesartan is available in the following strengths:

• 150 mg
• 300 mg

Drug Trade Names of Irbesartan

The brand names for irbesartan is Aprovel.

Mechanism of Action

Irbesartan is an angiotensin II receptor blocker.

Irbesartan relaxes and widens your blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body.

It is used to treat high blood pressure and heart failure. It helps to prevent future strokes, heart attacks and diabetic kidney disease.

If you have diabetic kidney disease, it helps to protect your kidneys and slows down the disease. It reduces high blood pressure and the amount of protein you lose through your kidneys.

Route of Administration

Irbesartan is given orally as tablets.

After a dose the hypotensive effect peaks within 3 to 6 hours and persists for at least 24 hours. The maximum hypotensive effect is achieved within 4 to 6 weeks after starting therapy.

Dosages

• For both high blood pressure and diabetic kidney disease
  • 150 mg to 300 mg, taken once a day.
• Over 75 year old, or have liver or kidney problems
  • The dose may be lower.
  • Initially 75 mg - 150 mg once a day.

Side Effects

Frequency	Adverse reactions
Common (≥1/100 to <1/10)	Musculoskeletal pain
	Nausea
	Vomiting
	Hypotension
	Hyperkalemia
Very rare (<1/10,000)	Dizziness
	Fatigue
	Cough
	Hyponatremia