Oxcarbazepine

Introduction

Carbamazepine is an anticonvulsant medication used primarily in the treatment of epilepsy. It has been used both alone and as add-on therapy for partial seizures with or without secondary generalization.

Generic Name 藥名	HA Code 藥物代碼	Classification藥物分類
		P1S1S3

Pronunciation

Oxcarbazepine 600mg

Mechanism of Action

Anticonvulsant medication. It is a sodium channel blocker. It binds to sodium channels and suppresses repetitive neuronal firing.

Dosage

1. Epilepsy

Oral	initially 300 mg twice daily increased according to response in steps of up to 600 mg daily at weekly intervals; usual dose rage 0.6 – 2.4 g daily in divided doses.

Administration in children

6 – 18 years	8 – 10 mg/kg daily in 2 divided doses increased according to response in steps of up to 10mg/kg daily at weekly intervals, to a maximum dose of 46 mg/kg daily. Usual maintenance doses in adjunctive therapy around 30mg/kg daily.