Diltiazem Hydrochloride
Diltiazem(中文:地爾硫卓) is a benzothiazepine calcium-channel blocker. It is used for:
a. Prevention and long-term treatment of angina.
b. Treatment of mild to moderate hypertension.
Pronunciation
Diltiazem hydrochloride controlled-released 100mg
Diltiazem hydrochloride controlled-released 30mg
Diltiazem hydrochloride controlled-released 60mg
| Generic Name: | Diltiazem |
|---|---|
| Brand Name: | HERBESSER |
| Class: | Cardiovascular Drug |
| Subclass: | Calcium-channel Blocker, CCB |
| Legal Classification: | P1S1S3 |
Drug Names
| Generic Name 藥物化學名稱 | HA Code 藥物代碼 | Legal Classification法律藥物分類 | Brand Name 品牌名稱 |
|---|---|---|---|
| Diltiazem HCL CR Tablet 30mg | DILT01 | P1S1S3 | HERBESSER |
| Diltiazem HCL CR Tablet 60mg | DILT02 | P1S1S3 | HERBESSER |
| Diltiazem HCL SR Capsule 100mg | DILT07 | P1S1S3 | HERBESSER |
| Diltiazem HCL SR Capsule 200mg | DILT08 | P1S1S3 | HERBESSER |
Mechanism of Action
Diltiazem is a peripheral and coronary vasodilator. It also inhibits cardiac conduction, particularly at the sino-atrial and atrioventricular nodes. Diltiazem works by lowering your blood pressure and makes it easier for your heart to pump blood around your body.
In angina, diltiazem works by improving the blood and oxygen supply to your heart. Angina is chest pain that comes on when not enough blood gets to the muscles of the heart. This usually happens because the arteries going to the heart become hardened and narrowed.
Route of Administration
Diltiazem is given orally in a sustained-release formulation.
Dosage
Your dose of diltiazem depends on why you need the medicine and what kind your doctor has prescribed. It is important to keep taking the same brand of diltiazem once you have started.
Agina
- BY MOUTH
- Adult: Initially 60 mg 3 times a day, adjusted according to response; maximum 360 mg per day.
- Elderly: initially 60 mg twice daily, adjusted according to response; maximum 360 mg per day (the heart rate should be monitored regularly and should not fall below 50 beats/minute).
Hypertension
- BY MOUTH
- Adult: an initial dose is 90 to 120 mg twice daily, increased as required to a maximum of 360 mg daily.
