Fludrocortisone

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Introduction

Fludrocortisone is a steroid with potent mineralocorticoid activity. It is used to treat:

  • adrenocortical insufficiency
  • postural hypotension
  • adrenogenital syndrome
Generic Name HA Code Legal Classification
Fludrocortisone Acetate Tablet 100mcg FLUD01 P1S1S3
Brand Name HK Reg Number Active Ingredients
FLORINEF TABLET 0.1mg


HK-00036 fludrocortisone acetate

Mechanism of Action

Fludrocortisone is a corticosteroid with glucocorticoid and highly potent mineralocorticoid activity.

Dosage

Fludrocortisone is used, usually with hydrocortisone, for replacement therapy in adrenocortical insufficiency. By Oral: as replacement therapy, 50-300 micrograms daily It is also given in the management of severe orthostatic hypotension, but hypokalaemia, fluid retention and supine hypertension may limit its use. It is used in eye ointment or ear drops in concentration of 0.1%.