Etodolac

Generic Name 藥名	HA Code 藥物代碼	Classification藥物分類
Etodolac Capsule 200mg		P1S1S3

Mechanism of Action

Anti-inflammatory agent, Non-steroidal anti-inflammatory drug (NSAID) selective COX-2 inhibitor

Dosage

In the treatment of rheumatoid arthritis and osteoarthritis:

Oral: initially 600 to 1000 mg daily in divided doses adjusted to response to a maintenance dose of 300 to 600 mg daily. Modified-release preparations are available for once-daily use in stable conditions.

For treatment of acute pain:

Oral: 200 to 400 mg every 6 to 8 hours, to a maximum of 1 g daily.

Piroxicam has been given in similar doses as a rectal suppository or on a short-term basis by intramuscular injection. Piroxicam is one of the few NSAIDs that can be given parenteral routes.

Administration in children

Etodolac has been used in children with juvenile idiopathic arthritis. The following doses, given according to body-weight, are recommended for children aged 6 years and over:

• 20 to 30 kg: 400 mg once daily
• 31 to 45 kg: 600 mg once daily
• 46 to 60 kg: 800 mg once daily
• Over 60 kg: 1 g once daily

Side Effects

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