Donepezil Hydrochloride
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Pronunciation
Donepezil hydrochloride 10mg (ARICEPT 10mg)
Donepezil hydrochloride 5mg (ARICEPT 5mg)
Introduction
Donepezil hydrochloride, is a reversible inhibitor of acetylcholinesterase. It is used for the treatment of mild to moderate dementia in Alzheimer’s disease.
| Generic Name 藥名 | HA Code 藥物代碼 | Classification藥物分類 |
|---|---|---|
| Donepezil HCL Tablet 5mg | DONE01 | P1S1S3 |
| Donepezil HCL Tablet 10mg | DONE02 | P1S1S3 |
| Donepezil HCL Orodispersible Tablet 5mg | DONE03 | P1S1S3 |
Mechanism of Action
Acetylcholinesterase inhibiting drug
Dosage
By Oral: initially 5 mg once daily at bedtime, increased if necessary, after one month to max. 10 mg daily.
Clinical benefit should be assessed on a regular basis. Up to half the patients will show a slower rate of cognitive decline. Donepezil should be discontinued in those not responding.
Side Effects
Common side effects include
• Nausea and vomiting • difficulty sleeping • aggression • Loss of appetite • Diarrhoea • Feeling tired • Muscle cramps
