Pethidine

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Pronunciation

Introduction

Pethidine, is a synthetic opioid analgesic that acts mainly as a -opioid agonist. Pethidine is used for the relief of most types of moderate to severe acute pain including the pain of labour. It is more lipid soluble than morphine and has a less potent and shorter lasting analgesic effect; analgesia usually lasts for 2 to 4 hours. Its short duration of action and accumulation of its neurotoxic metabolite make it unsuitable for the management of chronic pain.

Generic Name 藥名 HA Code 藥物代碼 Classification藥物分類
Pethidine 1ml injection PETH02 DD

Equivalent doses of opioid analgesics

Analgesic/Route Dose
Codeine: PO 100 mg
Diamorphine: IM, IV, SC 3 mg
Dihydrocodeine: PO 100 mg
Morphine: PO 10 mg
Morphine: IM, IV, SC 5 mg
Oxycodone: PO 6.6 mg
Tramadol: PO 100 mg
Route of Adminstration SC
IV