Buprenorphine
Buprenorphine is an opioid analgesic. It is used for the relief of moderate to severe pain and as an adjunct to anaesthesia. It is also used in the treatment of opioid dependence.
Transdermal buprenorphine patches is used for chronic intractable cancer pain and neuropathic pain. However, this route is not suitable for the treatment of acute pain.
| Generic Name 藥名 | HA Code 藥物代碼 | Classification藥物分類 |
|---|---|---|
| Burponorphine | DD |
Mechanism of Action
Pain relief
opioid dependence
| Route of Administration | IV |
|---|
Dosage
For chronic moderate to severe pain
Intramuscular : analgesia is apparent within 15 minutes and lasts up to 6 hours.
A slower, more prolonged response is achieved after sublingual doses. The analgesic effects of buprenorphine after transdermal application may not be seen for at least 12 to 24 hours.
Buprenorphine is given by all the above routes for relief of moderate and severe pain.
- Intramuscular or slow intravenous : 300 to 600 micrograms every 6 to 8 hours as required.
- Transmucosal : sublingual doses of 200 to 400 micrograms every 6 to 8 hours as required.
- Transdermal patches : doses should be individually titrated according to previous opioid usage. Patches are not appropriate for acute pain.
