Hydrocortisone

Pronunciation

Hydrocortisone 20mg

Introduction

Hydrocortisone is a steroid with anti-inflammatory and immunosuppressant effects. Indications include:

• Hypersensitivity reactions e.g. anaphylaxis and angioedema
• Asthma
• Inflammatory bowel disease
• Eczema, psoriasis and other inflammatory skin conditions
• Rheumatoid arthritis
• Treatment of choice for adrenocortical insufficiency

Hydrocortisone can be given by mouth, topically, or by injection.

Equivalent anti-inflammatory doses of steroids

Prednisolone 5 mg is equivalent to	Betamethasone 750 micrograms
	dexamethasone 750 micrograms
	hydrocortisone 20 mg
	methylprednisolone 4 mg
	triamcinolone 4 mg

Mechanism of Action

Immunosuppression agent, Steroid replacement agent, Anti-inflammatory agent

Generic Name 藥名	HA Code 藥物代碼	Classification藥物分類
Hydrocortisone Tablet 20mg	HYDR06	P1S1S3

Dosage

Hydrocortisone is used, usually with a more potent mineralocorticoid fludrocortisone, for replacement therapy in adrenocortical insufficiency.

By Oral: as replacement therapy, 20-30 mg daily (usually in 2 doses, the larger in the morning and the smaller in the early evening, to mimic the circadian rhythm of the body). By intramuscular injection or slow intravenous injection: 100-500 mg, 3-4 times in 24 hours or as required. Child dose: as replacement therapy in adrenocortical insufficiency,

By slow intravenous injection • Up to 1 year: 25 mg • 1-5 years: 50 mg • 6-12 years: 100 mg