Nitrazepam

Nitrazepam (中文:[[ ]])is a long-acting benzodiazepine. It is used as a hypnotic in the short-term management of insomnia. It is reported to act in 30 to 60 mionutes to produce sleep lasting for 6 to 8 hours.

Drug Names

Generic Name 藥名	HA Code 藥物代碼	Classification藥物分類
Nitrazepam Tablet 5 mg	NITR01	P1S1S3 & Part 1 Dangerous Drug

Mechanism of Action

• Nitrazepam is a benzodiazepine.
• Gama-Aminobutyric acid (GABA) is an inhibitory neurotransmitter, acting on the GABA receptors in the central nervous system (CNS), inducing sleepiness, muscular relaxation, and control of anxiety and seizures.
• Nitrazepam acts on the benzodiazepine receptors in the brain and the spinal cord. Benzodiazepine receptors in the CNS are linked with GABA receptors as a complex.
• Nitrazepam by binding to the benzodiazepine receptors results in activation of the GABA-benzodiazepine receptor complex.
• Thus, Nitrazepam helps to promote muscle relaxation, reduce anxiety, control of convulsions and promote sleep.