Galantamine

Introduction

Galantamine Hydrobromide, is a reversible inhibitor of acetylcholinesterase. It also has an intrinsic action on nicotinic receptors. It is used for the treatment of mild to moderate dementia in Alzheimer’s disease.

Generic Name 藥名	HA Code 藥物代碼	Classification藥物分類
Galantamine HBR Prolonged Release Cap 8mg	GALA04	P1S1S3
Galantamine HBR Prolonged Release Cap 16mg	GALA05	P1S1S3
Galantamine HBR Prolonged Release Cap 24mg	GALA06	P1S1S3

Mechanism of Action

Acetylcholinesterase inhibiting drug

Dosage

By Oral: initially 4 mg twice daily for 4 weeks increased to 8 mg twice daily for 4 weeks; maintenance 8-12 mg twice daily according to response and tolerance. A modified-release preparation is also available for once-daily use. Clinical benefit should be assessed on a regular basis. Reductions in dose may be necessary in patients with hepatic or renal impairment.