Candesartan: Difference between revisions
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*For children weighing less than 50kg, 4mg to 8mg once a day | *For children weighing less than 50kg, 4mg to 8mg once a day | ||
*For children weighing 50kg or more, 4mg to 16mg once a day | *For children weighing 50kg or more, 4mg to 16mg once a day | ||
==Side Effects== | |||
The following definitions of frequencies are used: | |||
Very common ≥ 1/10 | |||
Common ≥ 1/100 to < 1/10 | |||
Uncommon ≥ 1/1,000 to < 1/100 | |||
Rare ≥ 1/10,000 to < 1/1,000 | |||
Very rare < 1/10,000 | |||
{| class="wikitable" | |||
!style="text-align: left"| System Organ Class | |||
!Frequency | |||
!Adverse reactions | |||
|- | |||
|'''Nervous system disorders | |||
|Very rare | |||
|Dizziness, headache | |||
|- | |||
|'''Respiratory disorders | |||
|Very rare | |||
|cough | |||
|- | |||
|'''Skin disorders | |||
|Very rare | |||
|Pruritus, rash | |||
|- | |||
|'''Gastro-intestinal disorders | |||
|Very rare | |||
|Nausea | |||
|- | |||
|'''Vascular disorder | |||
|Common | |||
|Hypotension | |||
|- | |||
| rowspan="2" |'''Metabolism disorders | |||
|common | |||
|Hyperkalaemia | |||
|- | |||
|Very rare | |||
|hyponatraemia | |||
|} | |||
Revision as of 22:58, 23 August 2022
Candesartan (中文:坎地沙坦) is an angiotensin receptor blocker.
Pronunciation
Candesartan cilexetil Tablet 4mg
| Generic Name: | Candesartan |
|---|---|
| Class: | Cardiovascular Drug |
| Subclass: | angiotensin receptor blocker |
| Legal Classification: | P1S1S3 |
Drug Names
| Generic Name 藥物化學名稱 | HA Code 藥物代碼 | Legal Classification法律藥物分類 | Brand Name 藥名 |
|---|---|---|---|
| Candesartan cilexetil Tablet 4mg | CAND01 | P1S1S3 | BLOPRESS 8MG PLUS TAB 8/12.5MG (candesartan cilexetil 8mg + hydrochlorothiazide 12.5mg)
BLOPRESS 8MG PLUS TAB 16/12.5MG (candesartan cilexetil 16mg + hydrochlorothiazide 12.5mg) |
| Candesartan cilexetil Tablet 8mg | P1S1S3 | ||
| Candesartan cilexetil Tablet 16mg | P1S1S3 | ||
| Candesartan cilexetil Tablet 32mg | P1S1S3 |
Mechanism of Action
Candesartan relaxes and widens your blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. It is used to treat high blood pressure and heart failure. It helps to prevent future strokes, heart attacks and kidney problems. It also improves your survival if you are taking it for heart failure.
Route of Administration
Candesartan is given orally as the ester prodrug candesartan cilexetil which is rapidly converted to the active substance candesartan during absorption from the gastrointestinal tract. Onset of antihypertensive action occurs about 2 hours after a dose and the maximum effect is achieved within about 4 weeks of starting therapy.
Dosage
The dose of candesartan depends on why you need the medicine.
For adult, the usual dose is:
- High blood pressure – 8mg to 32mg once a day
- Heart failure – 4mg to 32mg once a day
For children (aged 6 years and over), the usual dose to treat high blood pressure is:
- For children weighing less than 50kg, 4mg to 8mg once a day
- For children weighing 50kg or more, 4mg to 16mg once a day
Side Effects
The following definitions of frequencies are used:
Very common ≥ 1/10
Common ≥ 1/100 to < 1/10
Uncommon ≥ 1/1,000 to < 1/100
Rare ≥ 1/10,000 to < 1/1,000
Very rare < 1/10,000
| System Organ Class | Frequency | Adverse reactions |
|---|---|---|
| Nervous system disorders | Very rare | Dizziness, headache |
| Respiratory disorders | Very rare | cough |
| Skin disorders | Very rare | Pruritus, rash |
| Gastro-intestinal disorders | Very rare | Nausea |
| Vascular disorder | Common | Hypotension |
| Metabolism disorders | common | Hyperkalaemia |
| Very rare | hyponatraemia |
