Felodipine

Felodipine(中文:非洛地平) is a dihydropyridine calcium-channel blocker. It is used in the management of hypertension and angina.

Pronunciation

Felodipine extended-release 2.5mg

Generic Name:	Felodipine
Brand Name:	PLENDIL
Class:	Cardiovascular Drug
Subclass:	Calcium-channel Blocker, CCB
Legal Classification:	P1S1S3

Drug Names

Generic Name 藥物化學名稱	HA Code 藥物代碼	Legal Classification法律藥物分類	Brand Name 品牌名稱
Felodipine Extended-Release Tablet 2.5mg	FELO03	P1S1S3	ADALAT RETARD TABLET
Felodipine Extended-Release Tablet 5mg	FELO01	P1S1S3	ADALAT RETARD TABLET

Mechanism of Action

Felodipine relaxes and widens blood vessels. It does this by blocking calcium going into muscles in the heart and blood vessels. Muscles need calcium to contract, so when you block the calcium, it makes the muscle cells relax. This lowers your blood pressure and makes it easier for your heart to pump blood around your body.

In angina, nifedipine works by improving the blood and oxygen supply to your heart. Angina is chest pain that comes on when not enough blood gets to the muscles of the heart. This usually happens because the arteries going to the heart become hardened and narrowed.

Route of Administration

Felodipine is given orally in an extended release formulation once daily.

Dosage

Agina

• BY MOUTH
• Adult: 5 mg daily, increased if necessary to 10 mg daily.

Hypertension

• BY MOUTH
• Adult: i5 mg daily, usual maintenance 5 – 10 mg once daily.

Elderly:initially 2.5 mg daily, to be taken in the morning; usual maintenance 5 – 10 mg once daily.